An ultra-sensitive UHPLC-MS/MS assay for the quantification of orally administered vancomycin in plasma

An ultra-sensitive UHPLC-MS/MS assay for the quantification of orally administered vancomycin in plasma

Innovative Grade US Origin Canine Beagle Plasma from Innovative Research was used in the following study:

 

An ultra-sensitive UHPLC-MS/MS assay for the quantification of orally administered vancomycin in plasma

Max Sauter, Philipp Uhl, Kathrin I. Foerster, Isabelle Mohr, Rahel T. Hönec, Uta Merlec, Jürgen Burhenne, Walter E. Haefeli

Journal of Pharmaceutical and Biomedical Analysis
27 June 2019

“…Vancomycin is a glyco-peptide antibiotic used intravenously for the treatment of gram-positive bacteria including multi-resistant Staphylococcus aureus and, as oral capsules, for the first-line treatment of gastro-intestinal Clostridium difficile infections (CDI). …Blank beagle plasma was purchased from Innovative Research (Novi, MI, USA)…”

 

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