Allosteric modulation of sigma receptors by BH3 mimetics ABT-737, ABT-263 (Navitoclax) and ABT-199 (Venetoclax)

Allosteric modulation of sigma receptors by BH3 mimetics ABT-737, ABT-263 (Navitoclax) and ABT-199 (Venetoclax)

Posted by Leanne Kodsmann on

Innovative Grade US Origin Rat Sprague Dawley Liver from Innovative Research was used in the following study:

 

Allosteric modulation of sigma receptors by BH3 mimetics ABT-737, ABT-263 (Navitoclax) and ABT-199 (Venetoclax)

John R. Lever, Emily A. Fergason-Cantrell

Pharmacological Research
Volume 142, April 2019, Pages 87-100

"... Membranes were prepared from frozen livers (Innovative Research, Inc.; Novi, MI) of male Sprague Dawley rats as detailed by Hellewell et al. [40]. Protein concentrations were determined using a bicinchoninic acid assay kit ..."

 

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  • Tags: Animal Tissues Organs, Innovative Grade US Origin Rat Sprague Dawley Liver

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