A quantitative LC–MS/MS method for determination of a small molecule agonist of EphA2 in mouse plasma and brain tissue

A quantitative LC–MS/MS method for determination of a small molecule agonist of EphA2 in mouse plasma and brain tissue

Posted by Leanne Kodsmann on

Mouse Non-Swiss Albino Plasma from Innovative Research was used in the following study:

 

A quantitative LC–MS/MS method for determination of a small molecule agonist of EphA2 in mouse plasma and brain tissue

Bo Zhong, Yaxin Li, Nethrie Idippily, Aaron Petty, Bin Su, Bingcheng Wang

Biomedical Chromatography
Volume 33 Issue 4 April 2019

"... Liquid-liquid extraction was used to extract the compound from mouse plasma and brain tissue homogenate. Reverse phase chromatograph with gradient elution was performed to separate compound 27 from the endogenous molecules in the matrix, followed by MS detection using positive ion multiple reaction monitoring (MRM) mode. ... Six different lots of Non Swiss Albino Mouse plasma were obtained from Innovative Research (Novi, MI) ..."

 

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  • Tags: Animal Plasma, Mouse Non Swiss Albino Plasma

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