A novel high-performance liquid chromatographic method combined with fluorescence detection for determination of ertugliflozin in rat plasma: Assessment of pharmacokinetic drug interaction potential of ertugliflozin with mefenamic acid and ketoconazole

A novel high-performance liquid chromatographic method combined with fluorescence detection for determination of ertugliflozin in rat plasma: Assessment of pharmacokinetic drug interaction potential of ertugliflozin with mefenamic acid and ketoconazole

Posted by Corey Marcath on

Innovative Grade US Origin Rat Sprague Dawley Plasma from Innovative Research was used in the following study:

 

A novel high-performance liquid chromatographic method combined with fluorescence detection for determination of ertugliflozin in rat plasma: Assessment of pharmacokinetic drug interaction potential of ertugliflozin with mefenamic acid and ketoconazole

Dong-Gyun Han, Hwayoung Yun, In-Soo Yoon

Journal of Chromatography B
25 May 2019

“…Type 2 diabetes mellitus (T2DM) is a metabolic disorder characterized by insulin resistance and the inability of the body to secrete sufficient insulin, resulting in high blood glucose levels [1]. A recent survey estimated that T2DM affected 415 million adults worldwide in 2015; this number is expected to increase to 642 million by 2040 …Pooled plasma from male Sprague-Dawley rats was purchased from Innovative Research, Inc. (Novi, MI, USA)…”

 

Related products available from Innovative Research also include:

  • Tags: Animal Plasma, Innovative Grade US Origin Rat Sprague Dawley Plasma

    • The next big thing: it's what you do. The biological research materials you need to discover it? That's what we do! We love seeing how our products are being used in real-life applications and contributing to scientific acheivements every day. With thousands of published references and decades of proven results, you can count on us to help you source the high-quality biomaterials you need that will deliver reliable, consistent results - kit to kit, lot to lot, all study long. So what are you waiting for? All great discoveries start somewhere... yours starts with Innovative Research! Get in touch with our team today!


    Related Posts

    Soft-sheath, stiff-core microfiber hydrogel for coating vascular implants
    Innovative Grade US Origin Bovine Plasma from Innovative Research was used in the follo...
    Read the Article
    Microsampling with cotton thread: Storage and ultra-sensitive analysis by thread spray mass Spectrometry
    Single Donor Human Whole Blood from Innovative Research was used in the following study...
    Read the Article

    ← Older Post Newer Post →