News
Label-free DNA Sensor for Detection of Bladder Cancer Biomarkers in Urine
Y Shin, AP Perera, MK Park - Sensors and Actuators B: Chemical, 2012For urine experiments, normal human urine was purchased from Innovative Research (Novi, MI) and stored at 4 C until used.
San Diego-based Fate Therapeutics, which focuses on the discovery and development of adult stem cell modulators, has announced that its Wnt protein therapeutic program, in development for use in skeletal muscle regeneration, has moved several steps closer to its goal.
After dealing with manufacture, formulation and delivery issues, Fate now has a selection of candidate proteins and has validated their therapeutic potential in a number of preclinical animal models. Naturally occurring proteins in the Wnt family are involved in stem cell fate and tissue development and repair.
Swedish drug developer Kancera says it has slowed the growth of pancreatic cancer tumors in preclinical animal trials with its first-generation PFKFB3 inhibitors.
The drug initially failed to work in an animal study involving human colon cancer, according to the company.
Amgen (AMGN) has an interesting new weapon in the battle againstobesity. The company's scientists successfully used an antibody they discovered to make obese monkeys thinner, and also lower their levels ofinsulin,glucoseand triglycerides.
Scientists at the Texas Biomedical Research Institute have big plans for a new treatment designed to help stop the transmission ofHIV.The San Antonio Express-News reports that in January they'll start testing a genetically engineeredvaccinein rhesus monkeys that interacts with epithelial stem cells to do its job.