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A new palm-sized microarray that holds 1,200 individual cultures of fungi or bacteria could enable faster, more efficient drug discovery, according to a study published inmBio, the online open-access journal of the American Society for Microbiology.

Scientists at the University of Texas at San Antonio and the U.S. Army Institute of Surgical Research at Fort Sam Houston have developed a microarray platform for culturing fungal biofilms, and validated one potential application of the technology to identify new drugs effective against Candida albicans biofilms.

While the cause and progression ofAlzheimer's diseaseremains unknown, scientists widely accept that amyloid beta plaque buildup leads to cognitive dysfunction associated with the disease.

Cell culture contamination has been a major concern for researchers since cell culture was introduced in the early 1900's. One particular villain to the field of in vitro research has been endotoxin. But what do we really know about it?

Enzyme-linked immunosorbent assay (ELISA) is a test that uses antibodies and color change to identify a substance. ELISA is a popular format of a "wet-lab" type analytic biochemistry assay that uses a solid-phase enzyme immunoassay (EIA) to detect the presence of a substance, usually an antigen, in a liquid sample or wet sample. The ELISA has been used as a diagnostic tool in medicine and plant pathology, as well as a quality-control check in various industries.

When carrying out research about humans and animals, you will discover that they both operate within procedures and established standards. However, the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research reports that the human research environment can be inefficient, operate with an imperfect process and even abuse some of their human subjects during research. No similar, principled and comprehensive effort has addressed the use of animals in research.