Human Factor XIIIa Purified
IHUFXIIIA250UGHuman Factor XIIIa Purified from Innovative Research has been produced from Human Factor XIII that has been cleaved with Immobilized Human alpha-Thrombin, then purified using chromatography to remove the Thrombin. This is a frozen liquid buffered in 50 mM Tris/ 100 mM NaCl/ 1 mM EDTA/ 10 u/mL aprotinin / 50 uM DTT/ 50% glycerol/ pH 7.5, with a concentration of 1mg/ml.
Factor XIII is activated to XIIIa by Thrombin (with Calcium as a cofactor). Factor XIIIa acts as a stablilzer for fibrin by catalyzing covalent bonds between fibrin molecules, leading to the development of a stable, elastic fibrin clot structure. A clot that has not been stabalized by FXIIIa is soluble, whereas a Factor XIIIa-stabilized clot is insoluble.
More Details:
- Source: Human Plasma
- Purification: Human Factor XIII was cleaved with resin-immobilized Human alpha-Thrombin, then purified using chromatography to remove the Thrombin.
- Storage Conditions: -20°C
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Please note – this product replaces our old product number IHFXIIIa (same product, new number).
These products are supplied for manufacturing, research and laboratory use only. Researchers and laboratory personnel intending to use any of these products for medical investigation on humans are solely responsible for such use and for compliance with the pertinent regulations of the United States Food and Drug Administration (US-FDA) and other regulations. We do not assume liability for damages resulting from the handling, use and/or disposal of these products, from their use in violation of patent or other rights or reliance upon this information.
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