Human Factor XII PurifiedIHUFXII500UG
Human Factor XII Purified from Innovative Research has been purified from human plasma. This is a frozen liquid buffered in 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3, with a concentration of 1mg/ml and a purity of greater than 95% as determined by SDS-PAGE analysis (no reduction when incubated with 2-mercaptoethanol).
Factor XII (Hageman Factor) is the zymogen form of Factor XIIa, and activates Factor XI and Prekallikrein. The activation of Factor XII to XIIa typically happens in the presence of polyphosphates secreted by activated platelets, marking the starting point of the Intrinsic Pathway of the coagulation cascade. In a laboratory setting, Factor XII can be used to activate a coagulation cascade.
- Source: Human Plasma
- Purity: > 95% by SDS-PAGE
- Storage Conditions: -60° to -80°C
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Please note – this product replaces our old product number IHFXII (same product, new number).
This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.
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