Rat Interleukin Assay and ELISA Kits

Rat IL-10 ELISA Kit

Catalog No.: IRKTAH2578


Category: Assay and ELISA Kits

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Product Description

Rat IL-10 ELISA Kit

Our Rat IL-10 ELISA Kit is a sandwich ELISA intended for the quantitative determination of rat IL-10 in cell culture supernates, serum and plasma (EDTA).

Interleukin-10, also called cytokine synthesis inhibitory factor, is implicated in tumorigenesis, and it has been shown that polymorphisms in its gene promoter correlate with differential amounts of production. IL-10 is an important cytokine with anti-inflammatory, anti-immune, and antifibrotic functions. It is also an important regulatory cytokine whose involvement extends into diverse areas of the human immune system. IL-10 is a recently described natural endogenous immunosuppressive cytokine that has been identified in human, murine, and other organisms. IL-10 significantly affects chemokine biology, because human IL-10 inhibits chemokine production and is a specific chemotactic factor for CD8 T cells. It suppresses the ability of CD4 T cells, but not CD8 T cells, to migrate in response to IL-8. Interleukin-10 gene polymorphisms and interleukin-10 production capability may contribute to the development of skin squamous cell carcinomas after renal transplantation. The interleukin-10 locus contributes to the heritability of psoriasis susceptibility. With regard to sudden infant death, IL-10 is of special interest. This is an immunoregulatory cytokine that plays an important role in the development of infectious disease. The mIL-10 gene is mapped to mouse chromosome 1 and the hIL-10 gene is also mapped to human chromosome 1.

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Rat IL-10 ELISA Kit

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