Rat TIMP-2 ELISA Kit - 1 Kit (96 Wells)Our Rat TIMP-2 ELISA Kit is a sandwich ELISA intended for the quantitative determination of rat TIMP-2 in cell culture supernates, serum and plasma (heparin, EDTA).
TIMP-2 gen is encoded by 5 exons spanning 83 kb of genomic DNA. TIMP-2 is 83 kilobase pairs (kb) long with exon-intron splicing sites located in preserved positions among the three members of the TIMP family. The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25. TIMP-2 abrogates angiogenic factor-induced endothelial cell proliferation in vitro and angiogenesis in vivo independent of MMP inhibition. The standard product used in this kit is recombinant human TIMP-2 with the molecular mass of 22Kda and 194 amino acid.