The Role of Type I Interferons in TLR7-Mediated Lupus and UVB-Induced Immune Cell Responses
Posted by Corey Marcath on
Mouse IgG ELIS A Kit from Innovative Research was used in the following study:
The Role of Type I Interferons in TLR7-Mediated Lupus and UVB-Induced Immune Cell Responses
Sonya Wolf-Fortune
deepblue.lib.umich.edu
2019
"...Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that is heterogeneous and multi-symptomatic, occurring in a series of flares in patients. Incidence worldwide ranges from 0.3 to 23.7 per 100,000 persons each year, and prevalence ranges from 6.5 to 178.0 per 100,000 persons2 . Geographically, higher incidence of SLE is found in Asia .0031%, Australia .093%, and the Americas .02%3, 4 . Complex interactions including gender and ethnic background contribute to the difference in incidence rate among SLE patients2…Serum was collected 2 weeks post UVB treatment. Anti-IgG and dsDNA IgG antibody levels were analyzed via ELISA kits (Alpha Diagnostic, San Antonio, TX, and Innovative Research, Novi, MI)…”
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