Product References — Pooled Human Serum Off The Clot

α-Synuclein in Blood Exosomes Immunoprecipitated Using Neuronal and Oligodendroglial Markers Distinguishes Parkinson’s Disease from Multiple System Atrophy

Posted by Adam Awdish on

α-Synuclein in Blood Exosomes Immunoprecipitated Using Neuronal and Oligodendroglial Markers Distinguishes Parkinson’s Disease from Multiple System Atrophy

Pooled Human Plasma (Blood Derived) and Pooled Human Serum Off the Clot from Innovative Research were used in the following study:   α-Synuclein in Blood Exosomes Immunoprecipitated Using Neuronal and Oligodendroglial Markers Distinguishes Parkinson’s Disease from Multiple System Atrophy Suman Dutta, Simon Hornung, Adira Kruayatidee, Katherine N. Maina, Irish del Rosario, Kimberly C. Paul, Darice Y. Wong, Aline Duarte Folle, Daniela Markovic, Jose-Alberto Palma, Geidy E. Serrano, Charles H. Adler, Susan L. Perlman, Wayne W. Poon, Un Jung Kang, Roy N. Alcalay, Miriam Sklerov, Karen H. Gylys, Horacio Kaufmann, Brent L. Fogel, Jeff M. Bronstein, Beate Ritz & Gal Bitan...

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Enhancement of Infectivity of Insect Cell-Derived La Crosse Virus by Human Serum

Posted by Adam Awdish on

Enhancement of Infectivity of Insect Cell-Derived La Crosse Virus by Human Serum

Pooled Human Serum Off The Clot from Innovative Research was used in the following study:   Enhancement of Infectivity of Insect Cell-Derived La Crosse Virus by Human Serum Maria A. Cruz, Griffith D. Parks Virus Research November 11, 2020 Innate cellular immune mechanisms are often the first line of defense a host organism has against viral infections. These include physical barriers like skin and mucous, antiviral inhibitors, signaling molecules such as interferon (IFN) and cytokines, etc. Some bodily fluids, such as serum, can demonstrate a broad range of antiviral activities and have been shown to act via a wide range...

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A Novel Method of High-Purity Extracellular Vesicle Enrichment from Microliter-scale Human Serum for Proteomic Analysis

Posted by Adam Awdish on

A Novel Method of High-Purity Extracellular Vesicle Enrichment from Microliter-scale Human Serum for Proteomic Analysis

Pooled Human Serum Off The Clot from Innovative Research was used in the following study:   A Novel Method of High-Purity Extracellular Vesicle Enrichment from Microliter-scale Human Serum for Proteomic Analysis Xiaohui Ji, Sisi Huang, Jie Zhang, Terri F. Bruce, Zhijing Tan, Donglin Wang, Jianhui Zhu, R. Kenneth Marcus, and David M. Lubman Electrophoresis November 9, 2020 Extracellular vesicles (EVs) are small, membrane-enclosed vesicles released by cells into extracellular spaces. EVs contain DNA, RNA, and proteins derived from their parent cell, and this combined with their size and ability to easily penetrate biological barriers makes them a unique and important...

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A Novel Transgenic Mouse Model for Corneal Scar Visualization

Posted by Adam Awdish on

A Novel Transgenic Mouse Model for Corneal Scar Visualization

Pooled Human Serum Off The Clot from Innovative Research was used in the following study:   A Novel Transgenic Mouse Model for Corneal Scar Visualization Irona Khandaker, James L. Funderburgh, Moira L. Geary, Martha L. Funderburgh, Vishal Jhanji, Yiqin Du, Gary Hin-Fai Yam Experimental Eye Research September 23, 2020 According to the WHO, vision loss affects over 2.2 billion people globally each year. Corneal opacification resulting from fibrotic scar tissue following infection or injury is a common cause of corneal blindness, and the standard treatment for persistent scar tissue is corneal transplantation of donor tissues. However, there are limitations hindering...

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Reduced Red Blood Cell Surface Level of Factor H as a Mechanism Underlying Paroxysmal Nocturnal Hemoglobinuria

Posted by Adam Awdish on

Reduced Red Blood Cell Surface Level of Factor H as a Mechanism Underlying Paroxysmal Nocturnal Hemoglobinuria

Pooled Human Serum Off The Clot from Innovative Research was used in the following study:   Reduced Red Blood Cell Surface Level of Factor H as a Mechanism Underlying Paroxysmal Nocturnal Hemoglobinuria Lingjun Zhang, Jin Y. Chen, Cassandra Kerr, Brian A. Cobb, Jaroslaw P. Maciejewski & Feng Lin Leukemia August 19, 2020 Complement is an important factor in the innate immune response that primarily acts to fight infection and clear apoptotic cells. Once activated, the complement cascade helps in the formation of membrane attack complexes (MAC, C5b-9) on the surfaces of pathogens, causing damage and even lysis of the intruding...

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