News — Factor IX

Factor IX is one of the proteins that play a role in coagulation. Produced in the liver and activated by Factor XIa or Factor VIIa, depending on whether the coagulation cascade is following the contact activation pathway or the tissue factor pathway, it then catalyzes the next reaction in the cascade continuing down the path toward clot formation. Factor IX deficiency results in Hemophilia B, a clotting disorder that prevents the blood from clotting appropriately.