{"product_id":"tfpi-recombinant-protein-his-tag-lyophilized","title":"TFPI Recombinant Protein His Tag Lyophilized","description":"\u003cp\u003eTFPI Recombinant Protein His Tag Lyophilized from Innovative Research has been recombinantly produced in HEK293 cells. This is a Lyophilized protein buffered in PBS, pH7.4 with a purity of \u0026gt;90% as determined by SDS-PAGE..\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTarget:\u003c\/b\u003e TFPI\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e \u0026gt;90% as determined by SDS-PAGE. \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e HEK293 cells \u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eStorage Conditions:\u003cb\u003e Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles. \u003c\/b\u003e\u003c\/b\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdditional Information:\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003eTissue factor pathway inhibitor (TFPI) is also known as Extrinsic pathway inhibitor (EPI), Lipoprotein - associated coagulation inhibitor (LACI), is a plasma proteinase inhibitor synthesized by vascular endothelial cells and part of it is associated with glycosaminoglycans of these cells. TFPI is a single-chain polypeptide which can reversibly inhibit Factor Xa (Xa) and Thrombin (Factor IIa). TFPI is a secreted protein with a N­terminal acidic region, three Kunitz (K) domains separated with by two linker regions, and a C­terminal basic region. The first K domain inhibits coagulation factor VIIa complexed to tissue factor (TF); The second K domain inhibits factor Xa; The third K domain binds to heparin; The C­terminal basic region may have several functions. For example, it plays an important role in binding of TFPI to cell surfaces.\u003cp\u003eThis recombinant protein can be used for WB. For research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.\u003c\/p\u003e","brand":"Innovative Research","offers":[{"title":"50ug","offer_id":40154456129732,"sku":"ITFPIRHISLY50UG","price":850.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/Enzymes-Proteins_4a21ec18-d6d2-45a6-a117-4074567d6101.png?v=1626492242","url":"https:\/\/www.innov-research.com\/products\/tfpi-recombinant-protein-his-tag-lyophilized","provider":"Innovative Research","version":"1.0","type":"link"}