{"product_id":"serpind1-recombinant-protein-his-tag-lyophilized","title":"SERPIND1 Recombinant Protein His Tag Lyophilized","description":"\u003cp\u003eSERPIND1 Recombinant Protein His Tag Lyophilized from Innovative Research has been recombinantly produced in HEK293 cells. This is a Lyophilized protein buffered in 50 mM Tris, 150 mM NaCl, pH 7.5 with a purity of \u0026gt;95% as determined by SDS-PAGE..\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTarget:\u003c\/b\u003e SERPIND1\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e \u0026gt;95% as determined by SDS-PAGE. \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e HEK293 cells \u003c\/li\u003e\n\u003cli\u003e\u003cb\u003eStorage Conditions:\u003cb\u003e Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles. \u003c\/b\u003e\u003c\/b\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdditional Information:\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003eSerpin D1 is also known as Heparin cofactor 2 (HCF2), Protease inhibitor leuserpin-2 (HLS2), Heparin cofactor II (HC-II), which belongs to the serpin family. HCF2 is expressed predominantly in liver. Thrombin inhibitor activated by the glycosaminoglycans, heparin or dermatan sulfate. In the presence of the latter, SerpinD1 \/ HC-II becomes the predominant thrombin inhibitor in place of antithrombin III (AT-III). In a glycosaminoglycan-independent manner, serpinD1 \/ HC-II also inhibits chymotrypsin. Peptides at the N-terminal of HC-II have chemotactic activity for both monocytes and neutrophils.\u003cp\u003eThis recombinant protein can be used for WB. For research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.\u003c\/p\u003e \u003cp\u003e\n\u003cbr\u003e\n\u003c\/p\u003e\u003cp\u003e\n\u003cbr\u003e\n\u003c\/p\u003e\u003cul style=\"list-style-type: circle;\"\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 11pt; color: rgb(0, 0, 0);\"\u003ePreheat a water bath to 37 C. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 11pt; color: rgb(0, 0, 0);\"\u003ePlace the frozen plasma sample directly in the water bath. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 11pt; color: rgb(0, 0, 0);\"\u003eGently agitate the plasma sample every 5-10 minutes to insure even thawing. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 11pt; color: rgb(0, 0, 0);\"\u003eThe total thawing time will depend on the frozen sample volume. A 10 ml sample might be thawed completely in 5 minutes, but a large sample could take up to 1 hour. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 11pt; color: rgb(0, 0, 0);\"\u003eThe thawed sample should be used immediately or stored at 4 C for up to 24 hours. Liquid plasma should never be kept on ice or stored below 0 C as the cold may cause clotting. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 11pt; color: rgb(0, 0, 0);\"\u003ePlasma should be visually inspected for signs of clotting or precipitation before use in experiments. A coagulation test such as aPTT can also be performed to verify the preservation of the hemostasis system. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 11pt; color: rgb(0, 0, 0);\"\u003ePlasma should always be snap-frozen by placing the tube in dry ice for at least 1 hour. Large containers can be covered in dry ice for even freezing. \u003c\/span\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cspan style=\"font-size: 11pt; color: rgb(0, 0, 0);\"\u003eFrozen plasma should be stored at –20 C or colder. Lower temperatures will help preserve labile plasma proteins for longer time periods. \u003c\/span\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp style=\"margin: 14px 0px;\"\u003e\u003cspan style=\"font-size:11.0pt;\"\u003e\u003cspan style=\"color: rgb(0, 0, 0);\"\u003e \u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\u003cp style=\"margin: 14px 0px;\"\u003e\u003cspan style=\"font-size: 11pt; color: rgb(0, 0, 0);\"\u003eThis protocol is applicable for plasma containing any anticoagulant of both human and animal origin. While handling serum does not involve the same risk of clotting due to improper handling, we recommend following the above instructions for both plasma and serum for best results\u003c\/span\u003e\u003c\/p\u003e\u003cp\u003e\n\u003cbr\u003e\n\u003c\/p\u003e","brand":"Innovative Research","offers":[{"title":"50ug","offer_id":40154425196740,"sku":"ISERPIND1RHISLY50UG","price":808.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/Enzymes-Proteins_2752842e-e05d-4ee9-9e67-d0261df7b0ec.png?v=1626492073","url":"https:\/\/www.innov-research.com\/products\/serpind1-recombinant-protein-his-tag-lyophilized","provider":"Innovative Research","version":"1.0","type":"link"}