{"product_id":"sars-cov-2-covid-19-s1-val16-arg685-recombinant-protein-c-fc-tag-lyophilized-100ug","title":"SARS-CoV-2 (COVID-19) S1 Val16-Arg685 Recombinant Protein C-Fc Tag Lyophilized","description":"\u003cp\u003eSARS-CoV-2 (COVID-19) S1 Val16-Arg685 Recombinant Protein C-Fc Tag Lyophilized from Innovative Research has been recombinantly produced in Mammalian cells. This is a Lyophilized protein buffered in Supplied as lyophilized from PBS, pH7.5 with a purity of \u0026gt;80% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue Staining..\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e SARS-CoV-2 \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTarget:\u003c\/b\u003e \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e \u0026gt;80% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue Staining. \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e Mammalian cells \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage Conditions:\u003c\/b\u003e Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt. \u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdditional Information:\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003eProtein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.\u003cp\u003eImmunogen. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.\u003c\/p\u003e","brand":"Innovative Research","offers":[{"title":"100UG","offer_id":40402773541060,"sku":"ICOV2S1VAL16ARG685RCFCLY100UG","price":902.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/files\/66211b8b-ccf5-459c-bd40-6ec9ff2c4d10_bbdb4a35-b081-4790-ac4d-040c1b297e05.jpg?v=1740021370","url":"https:\/\/www.innov-research.com\/products\/sars-cov-2-covid-19-s1-val16-arg685-recombinant-protein-c-fc-tag-lyophilized-100ug","provider":"Innovative Research","version":"1.0","type":"link"}