Rabbit Anti PRKAB2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (IHC,Immunofluorescence)IRBAMLPRKAB2AP427120UL
Rabbit Anti PRKAB2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (IHC,Immunofluorescence) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide, 50% glycerol, pH7.3 This antibody has been affinity purified.
- Host: Rabbit
- Species: Human,Mouse,Rat
- Target: PRKAB2
- Clonality: Polyclonal
- Purity: Affinity Purified
- Immunogen: Recombinant fusion protein of human PRKAB2 (NP_005390.1).
- Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene.
This product can be used in analytical tools such as IHC,Immunofluorescence.
At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.
For research use only.
This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.
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