Rabbit Anti PARP3 Polyclonal Affinity Purified (PBS with 0.02% sodium azide and 50% glycerol pH 7.4.) (Western Blot,IHC)IRBAMLPARP3AP125120UL
Rabbit Anti PARP3 Polyclonal Affinity Purified (PBS with 0.02% sodium azide and 50% glycerol pH 7.4.) (Western Blot,IHC) from Innovative Research is a polyclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide and 50% glycerol pH 7.4. This antibody has been affinity purified.
- Host: Rabbit
- Species: Human,Mouse,Rat
- Target: PARP3
- Clonality: Polyclonal
- Purity: Affinity Purified
- Immunogen: Recombinant human PARP3 protein
- Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles.
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing.
This product can be used in analytical tools such as Western Blot,IHC.
At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.
For research use only.
This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.
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