{"product_id":"mouse-profilin-toxoplasma-gondii-recombinant-protein-tag-free-lyophilized-10ug","title":"Mouse Profilin Toxoplasma gondii Recombinant Protein Tag Free Lyophilized","description":"\u003cp\u003eMouse Profilin Toxoplasma gondii Recombinant Protein Tag Free Lyophilized from Innovative Research has been recombinantly produced in E. coli. This is a Lyophilized protein buffered in Contains PBS. Reconstitute with 100 and#956;l sterile water. with a purity of \u0026gt;95% (SDS-PAGE).\u003cbr\u003e\u003cbr\u003e Endotoxin level is less than 0.01EU\/ and#956;g purified protein (LAL test; Lonza)..\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Mouse \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTarget:\u003c\/b\u003e \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e \u0026gt;95% (SDS-PAGE).\u003cbr\u003e\u003cbr\u003e Endotoxin level is less than 0.01EU\/ and#956;g purified protein (LAL test; Lonza). \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e E. coli \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage Conditions:\u003c\/b\u003e Stable for at least 6 months after receipt when stored at -20°C. \u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdditional Information:\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003eTLR11, an innate sensor for profilin (Toxoplasma gondii), is an intracellular receptor that resides in the endoplasmic reticulum. The 12 membrane-spanning endoplasmic reticulum-resident protein UNC93B1 interacts directly with TLR11 and regulates the activation of dendritic cells in response to profilin (Toxoplasma gondii) and parasitic infection in vivo. TLR12, a previously uncharacterized TLR, also recognizes profilin from Toxoplasma gondii. TLR12 is sufficient for recognition of profilin by plasmacytoid dendritic cells (pDCs), whereas TLR11 and TLR12 are both required in macrophages and conventional DCs. In contrast to TLR11, TLR12-deficient mice succumb rapidly to T. gondii infection.\u003cp\u003eThis recombinant proteins is for research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.\u003c\/p\u003e \u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cdiv style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; color: rgb(69, 69, 69); font-family: Inter, sans-serif; font-size: 16px; text-align: left;\" id=\"isPasted\"\u003eCurious About The Best Way To Thaw Plasma?\u003c\/div\u003e\u003cdiv style='user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; color: rgb(11, 9, 16); font-family: InterVariable, sans-serif, \"Apple Color Emoji\", \"Segoe UI Emoji\", \"Segoe UI Symbol\", \"Noto Color Emoji\"; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;'\u003e\u003cbr style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat;\"\u003e\u003c\/div\u003e\u003cdiv style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; color: rgb(69, 69, 69); font-family: Inter, sans-serif; font-size: 16px; text-align: left;\"\u003e\n\u003ca href=\"https:\/\/www.innov-research.com\/blogs\/news\/updated-video-resource-how-to-properly-thaw-plasma-samples\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eCheck out this\u003c\/a\u003e\u003cspan style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat;\"\u003e\u003ca href=\"https:\/\/www.innov-research.com\/blogs\/news\/updated-video-resource-how-to-properly-thaw-plasma-samples\" target=\"_blank\" rel=\"noopener noreferrer\"\u003e \u003c\/a\u003e\u003c\/span\u003e\u003ca href=\"https:\/\/www.innov-research.com\/blogs\/news\/updated-video-resource-how-to-properly-thaw-plasma-samples\" target=\"_blank\" rel=\"noopener noreferrer\"\u003eblog post\u003c\/a\u003e\n\u003c\/div\u003e\u003cdiv style='user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; color: rgb(11, 9, 16); font-family: InterVariable, sans-serif, \"Apple Color Emoji\", \"Segoe UI Emoji\", \"Segoe UI Symbol\", \"Noto Color Emoji\"; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;'\u003e\u003cbr style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat;\"\u003e\u003c\/div\u003e\u003cul style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; color: rgb(11, 9, 16); font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; list-style-position: inside; padding-left: 2rem; font-family: Inter, sans-serif; text-align: left; list-style-type: circle;\"\u003e\n\u003cli style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; list-style: inherit;\"\u003ePreheat a water bath to 37 C.\u003c\/li\u003e\n\u003cli style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; list-style: inherit;\"\u003ePlace the frozen plasma sample directly in the water bath.\u003c\/li\u003e\n\u003cli style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; list-style: inherit;\"\u003eGently agitate the plasma sample every 5-10 minutes to insure even thawing.\u003c\/li\u003e\n\u003cli style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; list-style: inherit;\"\u003eThe total thawing time will depend on the frozen sample volume. A 10 ml sample might be thawed completely in 5 minutes, but a large sample could take up to 1 hour.\u003c\/li\u003e\n\u003cli style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; list-style: inherit;\"\u003eThe thawed sample should be used immediately or stored at 4 C for up to 24 hours. Liquid plasma should never be kept on ice or stored below 0 C as the cold may cause clotting.\u003c\/li\u003e\n\u003cli style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; list-style: inherit;\"\u003ePlasma should be visually inspected for signs of clotting or precipitation before use in experiments. A coagulation test such as aPTT can also be performed to verify the preservation of the hemostasis system.\u003c\/li\u003e\n\u003cli style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; list-style: inherit;\"\u003ePlasma should always be snap-frozen by placing the tube in dry ice for at least 1 hour. Large containers can be covered in dry ice for even freezing.\u003c\/li\u003e\n\u003cli style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; list-style: inherit; margin-bottom: 0px;\"\u003eFrozen plasma should be stored at –20 C or colder. Lower temperatures will help preserve labile plasma proteins for longer time periods.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cdiv style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; color: rgb(11, 9, 16); font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; font-family: Inter, sans-serif; text-align: left;\"\u003e \u003c\/div\u003e\u003cdiv style='user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; color: rgb(11, 9, 16); font-family: InterVariable, sans-serif, \"Apple Color Emoji\", \"Segoe UI Emoji\", \"Segoe UI Symbol\", \"Noto Color Emoji\"; font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-align: start; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial;'\u003e\u003cbr style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat;\"\u003e\u003c\/div\u003e\u003cdiv style=\"user-select: initial; cursor: inherit; box-sizing: content-box; background-repeat: no-repeat; color: rgb(11, 9, 16); font-size: 14px; font-style: normal; font-variant-ligatures: normal; font-variant-caps: normal; font-weight: 400; letter-spacing: normal; orphans: 2; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; white-space: normal; background-color: rgb(255, 255, 255); text-decoration-thickness: initial; text-decoration-style: initial; text-decoration-color: initial; font-family: Inter, sans-serif; text-align: left;\"\u003eThis protocol is applicable for plasma containing any anticoagulant of both human and animal origin. While handling serum does not involve the same risk of clotting due to improper handling, we recommend following the above instructions for both plasma and serum for best results\u003c\/div\u003e","brand":"Innovative Research","offers":[{"title":"10UG","offer_id":40374191161540,"sku":"IMSPROFTOXOGONDIIRTFLY10UG","price":602.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/files\/66211b8b-ccf5-459c-bd40-6ec9ff2c4d10_35300694-ebe5-4fad-9d2c-09732cca646d.jpg?v=1740021096","url":"https:\/\/www.innov-research.com\/products\/mouse-profilin-toxoplasma-gondii-recombinant-protein-tag-free-lyophilized-10ug","provider":"Innovative Research","version":"1.0","type":"link"}