{"product_id":"mouse-ido-recombinant-protein-n-6-his-tag-50ug","title":"Mouse IDO Recombinant Protein N-6 His Tag","description":"Mouse IDO Recombinant Protein N-6 His Tag from Innovative Research has been recombinantly produced in E. coli. This is a Liquid protein buffered in Supplied as a 0.2 um filtered solution of 20mM Sodium Acetate, 150mM NaCl and 20% Glycerol, pH4.5.. It is not recommended to reconstitute to a concentration less than 100UG\/ml. with a purity of Greater than 95% as determined by reducing SDS-PAGE.Endotoxin level less than 0.1 ng\/?g (1 IEU\/?g) as determined by LAL test..More Details: Species: Mouse Target: Ido1 Purity: Greater than 95% as determined by reducing SDS-PAGE.Endotoxin level less than 0.1 ng\/?g (1 IEU\/?g) as determined by LAL test. Source: E. coli Storage Conditions: Store at -20░C, stable for 6 months after receipt.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. \u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdditional Information:\u003c\/strong\u003e\u003c\/p\u003eIndoleamine 2,3-dioxygenase (IDO) is a heme enzyme that initiates the oxidative degradation of the least abundant, essential amino acid, l-tryptophan, along the kynurenine pathway. This protein is normally expressed in the dendritic cells, macrophages, microglia, eosinophils, fibroblasts, endothelial cells, and most tumor cells. IDO activity is associated with immunosuppression and immune attenuation. Several studies showed that IDO can contribute to immune escape when expressed directly in tumor cells or when expressed in immunosuppressive antigen presenting cells such as tolerogenic dendritic cells or tumor associated macrophages. IDO also is a promising therapeutic target for the treatment of cancer, chronic viral infections, and other diseases characterized by pathological immune suppression.This recombinant protein can be used for biological assays. For research use only. . At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"50UG","offer_id":40681327689924,"sku":"IMSIDORN6HIS50UG","price":1091.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/files\/66211b8b-ccf5-459c-bd40-6ec9ff2c4d10_24a7ed68-5b73-4139-b660-7d23ae538133.jpg?v=1740023129","url":"https:\/\/www.innov-research.com\/products\/mouse-ido-recombinant-protein-n-6-his-tag-50ug","provider":"Innovative Research","version":"1.0","type":"link"}