{"product_id":"mouse-anti-human-active-casp3-monoclonal-clone-5a2","title":"Mouse Anti Human Active CASP3 Monoclonal Clone 5A2","description":"\u003cp\u003eMouse Anti Human Active CASP3 Monoclonal Clone 5A2 from Innovative Research is a monoclonal antibody in a liquid format, buffered in PBS with 0.02% sodium azide and 50% glycerol pH 7.4. This antibody has been purified using Protein A purification.\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eHost:\u003c\/b\u003e Mouse\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human,Mouse,Rat\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTarget:\u003c\/b\u003e CASP3\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eClonality:\u003c\/b\u003e Monoclonal\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eImmunogen:\u003c\/b\u003e Recombinant Protein\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage Conditions:\u003c\/b\u003e Store at -20°C. Avoid freeze \/ thaw cycles.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eInvolved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin.\u003c\/p\u003e\u003cp\u003eThis product can be used in analytical tools such as Western Blot,IHC-p,Immunofluorescence.\u003c\/p\u003e\u003cp\u003eAt Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.\u003c\/p\u003e\u003cp\u003eFor research use only.\u003c\/p\u003e","brand":"Innovative Research","offers":[{"title":"120ul","offer_id":40966241026244,"sku":"IMSAMLCASP35A2C120UL","price":276.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/files\/734844f0-9525-4b33-ad45-0c859a90882c_594fa652-398b-4691-a4c7-8820dcb4aa80.jpg?v=1740083856","url":"https:\/\/www.innov-research.com\/products\/mouse-anti-human-active-casp3-monoclonal-clone-5a2","provider":"Innovative Research","version":"1.0","type":"link"}