{"product_id":"miropin-protease-inhibitor","title":"*Miropin Protease Inhibitor","description":"\u003cp\u003eSelect this product for \u003cem\u003e\u003cstrong\u003eMolecular Innovations\u003c\/strong\u003e\u003c\/em\u003e name, \u003cb\u003eMiropin (Tannerella forsythia serine protease inhibitor)\u003c\/b\u003e and product number, \u003cb\u003eMIRO-HIS\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e Miropin Protease Inhibitor from Innovative Research is a prokaryotic serpin (SErine Protease INhibitor) protein from Tannerella forsythia, a human pathogen involved in the pathogenesis of periodontitis. Miropin can inhibit the activity of a broad range of proteases including trypsin, cathepsin G, neutrophil and pancreatic elastases. Therefore, miropin is a unique serpin in its wide range of inhibitory activity. Recombinantly produced in insect cell culture and purified by chelated metal affinity chromatography. Contains a 8X-Histidine tag at the N terminus for purification. This recombinant miropin inhibits the activity of human neutrophil elastase in vitro. At least 95% pure as determined by SDS-PAGE.\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e Insect Cells \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eGene ID:\u003c\/b\u003e 34759867 \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e T. forsythia \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSwiss-Prot\/UniProt ID:\u003c\/b\u003e G8UQY8 \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage:\u003c\/b\u003e -70C for up to 12 months \u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cb\u003eReferences:\u003c\/b\u003e\u003cbr\u003e1. Ksiazek, M., Mizgalska, D., Enghild, J.J., Scavenius, C.,Thogersen, I.B., and Potempa, J. Miropin, a Novel Bacterial Serpin from the Periodontopathogen Tannerella forsythia, Inhibits a Broad Range of Proteases by Using Different Peptide Bonds within the Reactive Center Loop. (2015) J. Biol. Chem. 290: 658-670.\u003c\/p\u003e\u003cp\u003eSelect this product for \u003cem\u003e\u003cstrong\u003eMolecular Innovations\u003c\/strong\u003e\u003c\/em\u003e name, \u003cb\u003eMiropin (Tannerella forsythia serine protease inhibitor)\u003c\/b\u003e and product number, \u003cb\u003eMIRO-HIS\u003c\/b\u003e\u003c\/p\u003e","brand":"Innovative Research","offers":[{"title":"10ug","offer_id":41363477463236,"sku":"IICMPPI10UG","price":207.0,"currency_code":"USD","in_stock":true},{"title":"50ug","offer_id":41363477496004,"sku":"IICMPPI50UG","price":525.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/EnzymeProteinsMolecular_a4a14559-93cb-45f4-92b1-c62e205f0dd4.jpg?v=1648841667","url":"https:\/\/www.innov-research.com\/products\/miropin-protease-inhibitor","provider":"Innovative Research","version":"1.0","type":"link"}