Innovative Grade Factor XII Knockout Mouse

Innovative Grade Factor XII Knockout Mouse

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  • $850.00
  • Featured Pricing


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Select this product for Molecular Innovations name, Factor XII Knockout Mouse and product number, MS-FXII.

At Innovative Research, we have worked to establish a broad range of working mouse research models to support many different therapeutic and disease areas of research. Our mouse models are fully licensed and maintained as live colonies on-site in our Novi, MI facility under the care of full-time animal husbandry staff as well as on-site scientific and veterinary care.

This allows us to quickly and easily provide you with the exact mouse models for research that you need, including knockout mice, transgenic mice, and more. 

Our live mouse research models are available as single, unique mice as well as breeding pairs with an annual breeding license (contact us for details on breeding pairs). We are able to accommodate most requests, including age and gender requirements.

Our Factor XII Knockout Mouse Models were created via targeted disruption of the F12 gene using CRISPR-Cas9 technology licensed from the Broad Institute of MIT and Harvard. Mutations were then confirmed using various methods, including PCR genotyping and Sanger sequencing, and the complete absence of Factor XII protein in the plasma of homozygous mice was confirmed by Western Blot. This research model is useful for a wide range of scientific studies, including research related to cardiovascular disease and neurological studies.

Our Factor XII Knockout Mouse Models are available as live homozygous mice. Coagulation Factor XII is also referred to as Hageman Factor.

Mouse Model Details:

  • Strain: C57BL6/SJL 
  • Chromosome: 13
  • Gene: F12
  • Genomic Target: Exon 8-12
  • Mutation: 1139 Base Pair Deletion
  • Phenotype: Complete absence of FXII protein

In addition to the live mouse models, we also offer a line of ready-to-use, genetically deficient plasma, organs, and tissue lysates that are ideal for use in applications like ELISA, Western Blot, and more. At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.

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