{"product_id":"human-sil-4-receptor-alpha-recombinant-protein-lyophilized-5ug","title":"Human sIL-4 Receptor alpha Recombinant Protein Lyophilized","description":"\u003cp\u003eHuman sIL-4 Receptor alpha Recombinant Protein Lyophilized from Innovative Research has been recombinantly produced in CHO cells. This is a Lyophilized protein buffered in with a purity of ? 95% by SDS-PAGE gel and HPLC analyses..\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTarget:\u003c\/b\u003e IL4R\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e ? 95% by SDS-PAGE gel and HPLC analyses. \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e CHO cells \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage Conditions:\u003c\/b\u003e The recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing the recombinant protein to repeated freeze \/ thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. \u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdditional Information:\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003eIL-4 can signal through type I and type II receptor complexes, which share a common gamma chain (?c). The type I receptor contains, in addition to the ?c, an IL-4R? subunit, whereas the type II receptor contains the IL-13R?. The secreted extracellular domain of IL-4R?, called sIL-4R?, binds IL-4 and anTagonizes its activity. It plays an important role in regulating the differentiation of naïve CD4+ T cells and class switching to IgG1 and IgE. CHO cell-derived Recombinant Human sIL-4 Receptor ? is a 23.9 kDa glycoprotein corresponding to 209 amino acid residues of the extracellular domain of IL-4R?. As a result of glycosylation, Recombinant Human sIL-4 Receptor ? migrates with an apparent molecular mass of approximately 50-65 kDa by SDS-PAGE gel, under reducing conditions.\u003cp\u003e. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.\u003c\/p\u003e","brand":"Innovative Research","offers":[{"title":"5UG","offer_id":40752214835396,"sku":"IHUSIL4ARLY5UG","price":336.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/Enzymes-Proteins_f82de256-804d-4042-b981-5735795d126c.png?v=1633705611","url":"https:\/\/www.innov-research.com\/products\/human-sil-4-receptor-alpha-recombinant-protein-lyophilized-5ug","provider":"Innovative Research","version":"1.0","type":"link"}