{"product_id":"human-mouse-april-aa-98-233-h98-multimeric-recombinant-protein-ddddk-tag-lyophilized-10ug","title":"Human \/ Mouse APRIL (aa 98-233) H98 multimeric Recombinant Protein DDDDK Tag Lyophilized","description":"\u003cp\u003eHuman \/ Mouse APRIL (aa 98-233) H98 multimeric Recombinant Protein DDDDK Tag Lyophilized from Innovative Research has been recombinantly produced in HEK293 cells. This is a Lyophilized protein buffered in Contains PBS + 0.5% Trehalose. Reconstitute with 100 and#956;l sterile water. with a purity of \u0026gt;95% (SDS-PAGE).\u003cbr\u003e\u003cbr\u003e Endotoxin level is less than 0.01EU\/ and#956;g purified protein (LAL test; Lonza)..\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human, Mouse \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTarget:\u003c\/b\u003e TNFSF13\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e \u0026gt;95% (SDS-PAGE).\u003cbr\u003e\u003cbr\u003e Endotoxin level is less than 0.01EU\/ and#956;g purified protein (LAL test; Lonza). \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e HEK293 cells \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage Conditions:\u003c\/b\u003e Stable for at least 6 months after receipt when stored at -20°C. \u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdditional Information:\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003eAPRIL is a cytokine that belongs to the TNF superfamily and binds to TACI and BCMA. It is implicated in the regulation of tumor cell growth, is involved in monocyte\/macrophage-mediated immunological processes and functions as an important survival factor for plasmablasts and bone marrow plasma cells. MultimericAPRIL™ is a high activity construct in which two trimeric APRIL ligands are artificially linked via the collagen domain of ACRP30. This construct very effectively stimulates proliferation B cell. A basic amino acid sequence (QKQKKQ) close to the N-terminal of APRIL is required for binding to negatively charged sulfated glycosaminoglycan side chains of proteoglycans. Proteoglycans mediate binding of APRIL to tumor cells as well as primary lymphoid cells.\u003cp\u003eThis recombinant proteins is for research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.\u003c\/p\u003e","brand":"Innovative Research","offers":[{"title":"10UG","offer_id":40374182150340,"sku":"IHUMSAPRILAA98233H98MULTIRDDDDKLY10UG","price":764.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/files\/66211b8b-ccf5-459c-bd40-6ec9ff2c4d10_dfe7f3d2-4db1-4b62-b701-42d1fddc4825.jpg?v=1740021065","url":"https:\/\/www.innov-research.com\/products\/human-mouse-april-aa-98-233-h98-multimeric-recombinant-protein-ddddk-tag-lyophilized-10ug","provider":"Innovative Research","version":"1.0","type":"link"}