{"product_id":"human-lmcd1-recombinant-protein-n-c-6-his-tag-50ug","title":"Human LMCD1 Recombinant Protein N, C-6 His Tag","description":"Human LMCD1 Recombinant Protein N, C-6 His Tag from Innovative Research has been recombinantly produced in E. coli. This is a Liquid protein buffered in Supplied as a 0.2 um filtered solution of 20mM PB?150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100UG\/ml. with a purity of Greater than 95% as determined by reducing SDS-PAGE.Endotoxin level less than 0.1 ng\/ug (1 IEU\/ug) as determined by LAL test..More Details: Species: Human Target: LMCD1 Purity: Greater than 95% as determined by reducing SDS-PAGE.Endotoxin level less than 0.1 ng\/ug (1 IEU\/ug) as determined by LAL test. Source: E. coli Storage Conditions: Store at -20░C, stable for 6 months after receipt.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. \u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdditional Information:\u003c\/strong\u003e\u003c\/p\u003eLMCD1 is transcriptional cofactor which contains a cysteine-rich domain in the N-terminal region and 2 LIM domains in the C-terminal region. It also has several potential phosphorylation and N-myristoylation sites and a single potential N-glycosylation site. LMCD1 is expressed in many tissues with highest abundance in skeletal muscle. LMCD1 restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. It plays a critical role in the development of cardiac hypertrophy via activation of calcineurin\/nuclear factor of activated T-cells signaling pathway.This recombinant protein can be used for biological assays. For research use only. . At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"50UG","offer_id":40599495704772,"sku":"IHULMCD1RNC6HIS50UG","price":1091.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/Enzymes-Proteins_c90af110-d0c9-41da-8a03-0590d03888cd.png?v=1631296339","url":"https:\/\/www.innov-research.com\/products\/human-lmcd1-recombinant-protein-n-c-6-his-tag-50ug","provider":"Innovative Research","version":"1.0","type":"link"}