{"product_id":"human-endoglin-recombinant-protein-n-trx-6-his-tag-50ug","title":"Human Endoglin Recombinant Protein N-Trx, 6 His Tag","description":"Human Endoglin Recombinant Protein N-Trx, 6 His Tag from Innovative Research has been recombinantly produced in E. coli. This is a Liquid protein buffered in Supplied as a 0.2 um filtered solution of 20mM PB?150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100UG\/ml. with a purity of Greater than 95% as determined by reducing SDS-PAGE.Endotoxin level less than 0.1 ng\/ug (1 IEU\/ug) as determined by LAL test..More Details: Species: Human Target: ENG Purity: Greater than 95% as determined by reducing SDS-PAGE.Endotoxin level less than 0.1 ng\/ug (1 IEU\/ug) as determined by LAL test. Source: E. coli Storage Conditions: Store at -20░C, stable for 6 months after receipt.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. \u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdditional Information:\u003c\/strong\u003e\u003c\/p\u003eEndoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and\/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins and\/or other RGD receptors. Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1), which is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations. This recombinant protein can be used for biological assays. For research use only. . At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"50UG","offer_id":40599494000836,"sku":"IHUENDGRNTRX6HIS50UG","price":808.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/Enzymes-Proteins_82494ae3-f305-4679-95c5-fcb3122d6e5b.png?v=1631296324","url":"https:\/\/www.innov-research.com\/products\/human-endoglin-recombinant-protein-n-trx-6-his-tag-50ug","provider":"Innovative Research","version":"1.0","type":"link"}