{"product_id":"human-cd172a-recombinant-protein-c-fc-tag-lyophilized","title":"Human CD172a Recombinant Protein C-Fc Tag Lyophilized","description":"\u003cp\u003eHuman CD172a Recombinant Protein C-Fc Tag Lyophilized from Innovative Research has been recombinantly produced in Human Cells. The protein formulation is lyophilized from a 0.2 ?m filtered solution of PBS, pH7.4. with a purity of \u0026gt; 95 % as determined by reducing SDS-PAGE..\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTarget:\u003c\/b\u003e CD172a\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e \u0026gt; 95 % as determined by reducing SDS-PAGE..\u0026lt; 1.0 EU per ug as determined by the LAL method.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e Human Cells\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage Conditions:\u003c\/b\u003e Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20? for 3 months.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eSignal Regulatory Protein ? (SIRP?) is a monomeric approximately 90 kD type I transmembrane glycoprotein. The 504 amino acid human SIRP? contains two Ig-like C1-type domains and one Ig-like V-type domain. SIRP? can express in various tissues, mainly on brain and myeloid cells, including macrophages, neutrophils, dendritic and Langerhans cells. It also can detect in neurons, smooth muscle and endothelial cells. SIRPA is an immunoglobulin-like cell surface receptor for CD47. SIRP? acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. SIRP? shows adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. SIRP? engagement generally produces a negative regulatory signal; it may mediate negative regulation of phagocytosis, mast cell activation and dendritic cell activation\u003c\/p\u003e\u003cp\u003eAt Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.\u003c\/p\u003e\u003cp\u003eFor research use only.\u003c\/p\u003e","brand":"Innovative Research","offers":[{"title":"10ug","offer_id":41176613650628,"sku":"IHUSIRPARCFCLY10UG","price":141.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/files\/66211b8b-ccf5-459c-bd40-6ec9ff2c4d10_7e5e9b54-6971-4ca2-85f4-e85405d797e9.jpg?v=1740024243","url":"https:\/\/www.innov-research.com\/products\/human-cd172a-recombinant-protein-c-fc-tag-lyophilized","provider":"Innovative Research","version":"1.0","type":"link"}