{"product_id":"human-butyrylcholinesterase-recombinant-protein-c-6his-tag","title":"Human Butyrylcholinesterase Recombinant Protein C-6His Tag","description":"\u003cp\u003eHuman Butyrylcholinesterase Recombinant Protein C-6His Tag from Innovative Research has been recombinantly produced in Human Cells. The protein formulation is supplied as a 0.2 ?m filtered solution of 20mM TrisHCl, 150mM NaCl, pH 7.5. with a purity of \u0026gt; 95 % as determined by reducing SDS-PAGE..\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTarget:\u003c\/b\u003e Butyrylcholinesterase\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e \u0026gt; 95 % as determined by reducing SDS-PAGE..\u0026lt; 1.0 EU per ug as determined by the LAL method.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e Human Cells\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage Conditions:\u003c\/b\u003e Store at \u0026lt; -20°C, stable for 6 months. Please minimize freeze-thaw cycles.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eButyrylcholine Esterase (BCHE) is a secreted protein that belongs to the type-B carboxylesterase\/lipase family. BCHE is a major acetylcholine hydrolyzing enzyme in the circulation. It is detected in blood plasma and present in most cells except erythrocytes. BCHE is an esterase with broad substrate specificity. BCHE can contribute to the inactivation of the neurotransmitter acetylcholine. BCHE can degrade a large number of neurotoxic organophosphate esters. Thus, it plays important pharmacological and toxicological roles and is thought to be involved in the pathological progression. Defects in BCHE are the cause of butyrylcholinesterase deficiency (BChE deficiency) which is a metabolic disorder characterized by prolonged apnoea after the use of certain anesthetic drugs, including the muscle relaxants succinylcholine and other ester local anesthetics.\u003c\/p\u003e\u003cp\u003eAt Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.\u003c\/p\u003e\u003cp\u003eFor research use only.\u003c\/p\u003e","brand":"Innovative Research","offers":[{"title":"10ug","offer_id":41176611061956,"sku":"IHUBCHERC6HIS10UG","price":394.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/files\/66211b8b-ccf5-459c-bd40-6ec9ff2c4d10_af102402-8839-4ab7-a8bb-ddbf51c64928.jpg?v=1740024213","url":"https:\/\/www.innov-research.com\/products\/human-butyrylcholinesterase-recombinant-protein-c-6his-tag","provider":"Innovative Research","version":"1.0","type":"link"}