{"product_id":"human-bmp-2-non-lytic-recombinant-protein-fc-tag-lyophilized-50ug","title":"Human BMP-2 non-lytic Recombinant Protein Fc Tag Lyophilized","description":"Human BMP-2 non-lytic Recombinant Protein Fc Tag Lyophilized from Innovative Research has been recombinantly produced in CHO cells. This is a Lyophilized protein buffered in Lyophilized from 0.2um-filtered solution in PBS. Reconstitute in 50 and#956;l sterile water. Add 1X PBS to the desired protein concentration. with a purity of \u0026gt;98% (SDS-PAGE). Endotoxin level is less than 0.06EU\/ and#956;g protein (LAL test; Lonza)..More Details: Species: Human Target: BMP2 Purity: \u0026gt;98% (SDS-PAGE). Endotoxin level is less than 0.06EU\/ and#956;g protein (LAL test; Lonza). Source: CHO cells Storage Conditions: Stable for at least 1 year after receipt when stored at -20░C. Working aliquots are stable for up to 3 months when stored at -20░C. \u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdditional Information:\u003c\/strong\u003e\u003c\/p\u003eBone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGF-beta superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation and bone formation and regeneration. BMP-2 signals through heterodimeric complexes composed of a type I receptor (Activin RI, BMP-RIA or BMP-RIB) and a type II receptor (BMP-RII or Activin RIIB). BMP-2 induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth and bone and cartilage repair. It induces ectopic bone formation or calcification by promoting osteogenic and chondrogenic differentiation in mesenchymal cells, stem cells and vascular smooth muscle cells. It also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells and is required for cardiac contractility.This recombinant proteins is for research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.","brand":"Innovative Research","offers":[{"title":"50UG","offer_id":40374201811140,"sku":"IHUBMP2NONLYTICRFCLY50UG","price":902.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/Enzymes-Proteins_3d24b749-516c-4f89-bee8-8ce6d374d922.png?v=1628886725","url":"https:\/\/www.innov-research.com\/products\/human-bmp-2-non-lytic-recombinant-protein-fc-tag-lyophilized-50ug","provider":"Innovative Research","version":"1.0","type":"link"}