{"product_id":"human-adiponectin-recombinant-protein-c-6his-tag-lyophilized","title":"Human Adiponectin Recombinant Protein C-6His Tag Lyophilized","description":"\u003cp\u003eHuman Adiponectin Recombinant Protein C-6His Tag Lyophilized from Innovative Research has been recombinantly produced in Human Cells. The protein formulation is lyophilized from a 0.2 ?m filtered solution of 20mM PB, 150mM NaCl, pH 7.2. with a purity of \u0026gt; 90 % as determined by reducing SDS-PAGE..\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Human\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTarget:\u003c\/b\u003e Adiponectin\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e \u0026gt; 90 % as determined by reducing SDS-PAGE..\u0026lt; 1.0 EU per ug as determined by the LAL method.\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e Human Cells\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage Conditions:\u003c\/b\u003e Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8? for 2-7 days. Aliquots of reconstituted samples are stable at \u0026lt; -20? for 3 months.\u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003eAdiponectin is a secreted protein. It is synthesized exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Adiponectin also antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.\u003c\/p\u003e\u003cp\u003eAt Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.\u003c\/p\u003e\u003cp\u003eFor research use only.\u003c\/p\u003e","brand":"Innovative Research","offers":[{"title":"10ug","offer_id":41176608407748,"sku":"IHUADIPOQRC6HISLY10UG","price":119.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/files\/66211b8b-ccf5-459c-bd40-6ec9ff2c4d10_04e5a3e3-786b-4c92-b8a8-4df3cbcc3aa1.jpg?v=1740024188","url":"https:\/\/www.innov-research.com\/products\/human-adiponectin-recombinant-protein-c-6his-tag-lyophilized","provider":"Innovative Research","version":"1.0","type":"link"}