Canine Interleukin-1 Beta (IL-1b) RecombinantICNIL1BR5UG
Canine Interleukin-1 Beta (IL-1b) Recombinant from Innovative Research has been recombinantly produced in yeast and purified using ion-exchange chromatography. This is a loyphilized powder with a purity of greater than 95% as determined by SDS-PAGE analysis.
This product is endotoxin free, naturally folded, and pos-translationally modified. This product can be used in cell culture, as an ELISA Standard for IL-1b, and as a Western Blot control. Interleukin-1 Beta is a member of the Interleukin 1 family of cytokines, a group that plays a part in regulating immune and inflammatory responses in the body. IL-1b is syntheszied as a precursor form protein following stimulation of innate immune cells by Toll-like receptors or RIG-like receptors. The IL-1b precursor needs to be cleaved by caspase-1 in order to induce binding abilities, and caspase needs to be activated by the inflammasome (mediated by sytoplasmic pattern recognition receptor signaling). As a result, the secretion of IL-1b is dependent on the necessary steps and activation of the appropriate receptors in order to become active itself.
- Source: Yeast Culture
- Purification: Ion Exchange Chromatography
- Purity: > 95% by SDS-PAGE
- Storage Conditions: -20°C
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Please note – this product replaces our old product number IRKFAP0123 (same product, new number).
These products are supplied for manufacturing, research and laboratory use only. Researchers and laboratory personnel intending to use any of these products for medical investigation on humans are solely responsible for such use and for compliance with the pertinent regulations of the United States Food and Drug Administration (US-FDA) and other regulations. We do not assume liability for damages resulting from the handling, use and/or disposal of these products, from their use in violation of patent or other rights or reliance upon this information.
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