Canine Interleukin-1 Beta (IL-1b) RecombinantICNIL1BR5UG
Canine Interleukin-1 Beta (IL-1b) Recombinant from Innovative Research has been recombinantly produced in yeast and purified using ion-exchange chromatography. This is a loyphilized powder with a purity of greater than 95% as determined by SDS-PAGE analysis.
This product is endotoxin free, naturally folded, and pos-translationally modified. This product can be used in cell culture, as an ELISA Standard for IL-1b, and as a Western Blot control. Interleukin-1 Beta is a member of the Interleukin 1 family of cytokines, a group that plays a part in regulating immune and inflammatory responses in the body. IL-1b is syntheszied as a precursor form protein following stimulation of innate immune cells by Toll-like receptors or RIG-like receptors. The IL-1b precursor needs to be cleaved by caspase-1 in order to induce binding abilities, and caspase needs to be activated by the inflammasome (mediated by sytoplasmic pattern recognition receptor signaling). As a result, the secretion of IL-1b is dependent on the necessary steps and activation of the appropriate receptors in order to become active itself.
- Source: Yeast Culture
- Purification: Ion Exchange Chromatography
- Purity: > 95% by SDS-PAGE
- Storage Conditions: -20°C
At Innovative Research, we provide reliable, consistent products that deliver reliable, consistent results.
Please note – this product replaces our old product number IRKFAP0123 (same product, new number).
This material is sold for in-vitro use only for manufacturing and research. This material is not suitable for human or animal use. While we make every effort to ensure the safety of our products, we recommend handling any biological materials with standard precautions as if capable of spreading infectious disease. The statements herin are offered for informational purposes only to be used solely for your consideration, investigation, and verification.
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