{"product_id":"bacteria-derived-clusterin-nuclear-form-recombinant-protein-his-tag","title":"Bacteria-Derived Clusterin nuclear form Recombinant Protein His Tag","description":"\u003cp\u003eBacteria-Derived Clusterin nuclear form Recombinant Protein His Tag from Innovative Research has been recombinantly produced in E. coli. This is a Liquid protein buffered in 0.2um-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. with a purity of \u0026gt;90% (SDS-PAGE).\u003cbr\u003e\u003cbr\u003e Endotoxin level is less than 1EU\/ and#956;g purified protein (LAL test; Lonza)..\u003c\/p\u003e\u003cp\u003e\u003cb\u003e\u003ci\u003eMore Details:\u003c\/i\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cul\u003e\n\u003cli\u003e\n\u003cb\u003eSpecies:\u003c\/b\u003e Bacteria-Derived \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eTarget:\u003c\/b\u003e CLU\u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003ePurity:\u003c\/b\u003e \u0026gt;90% (SDS-PAGE).\u003cbr\u003e\u003cbr\u003e Endotoxin level is less than 1EU\/ and#956;g purified protein (LAL test; Lonza). \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eSource:\u003c\/b\u003e E. coli \u003c\/li\u003e\n\u003cli\u003e\n\u003cb\u003eStorage Conditions:\u003c\/b\u003e Working aliquots are stable for up to 3 months when stored at -20°C. \u003c\/li\u003e\n\u003c\/ul\u003e\u003cp\u003e\u003cb\u003e\u003c\/b\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cbr\u003e\u003c\/p\u003e\u003cp\u003e\u003cstrong\u003eAdditional Information:\u003c\/strong\u003e\u003c\/p\u003e\u003cbr\u003eClusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80-kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all human fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.\u003cp\u003eThis recombinant proteins is for research use only.. At Innovative Research we provide reliable, consistent products that deliver reliable, consistent results.\u003c\/p\u003e","brand":"Innovative Research","offers":[{"title":"50UG","offer_id":40245502574788,"sku":"IBCTCLSNUCFRHIS50UG","price":808.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0050\/2297\/4065\/products\/Enzymes-Proteins_5cc18f45-56a4-457b-b28a-93baaf82b028.png?v=1627670866","url":"https:\/\/www.innov-research.com\/products\/bacteria-derived-clusterin-nuclear-form-recombinant-protein-his-tag","provider":"Innovative Research","version":"1.0","type":"link"}