Rat Plasma

Sprague Dawley Rat Plasma

Catalog No.: IRT-N

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Category: Plasma

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Product Description

Sprague Dawley Rat Plasma

Innovative Research's Sprague Dawley Rat Plasma is manufactured from whole blood collections from Sprague Dawley Rats.

Our Sprague Dawley Rat Plasma is manufactured in large batches and is not available with any special instructions. If you require custom collected material, please see our Premium US Origin Sprague Dawley Rat Plasma.

This Innovative Research product is for in vitro research use only, is not to be consumed by animals or humans, and should be handled with general precaution as if capable of spreading infectious disease.

Plasma ameliorates endothelial dysfunction in burn injury

Mariana Vigiola Cruz MD, Bonnie C. Carney BS, Jenna N. Luker MD, Kyle W. Monger BS, Juan Sebastian Vazquez MD, Lauren T. Moffatt PhD, Laura S. Johnson MD, Jeffrey W. Shupp MD
Journal of Surgical Research, January 2019

" ... Sprague-Dawley rats were used to create small, medium, and large burns and uninjured controls. Three different intravenous resuscitation protocols were applied within each group: Lactated Ringer's (LR) alone, LR plus fresh frozen plasma (FFP), or LR plus albumin... In the LR plus FFP group, animals were resuscitated identically to the LR-only group, except they were given a 0.45 mL intravenous injection of rat FFP (Innovative Research, Inc, Novi, MI) immediately after burn ("hour 0"), and at hours 2, 4, and 8.


HPLCelectrospray mass spectrometric assay for the determination of (R, R)-fenoterol in rat plasma

D Siluk, HS Kim, T Cole... - Journal of pharmaceutical and ..., 2008 - Elsevier
...Purified water was prepared using a Milli-Q system (Millipore, Milford, MA). Control rat plasma collected from whole blood onto sodium EDTA was purchased from Innovative Research (Novi, MI). 2.2. Chromatographic conditions.


Pharmacokinetics and metabolism of (R, R)-methoxyfenoterol in rat

D Siluk, DE Mager, HS Kim, Y Wang... - ..., 2010 - informahealthcare.com
...Pittsburgh, PA, USA). Purified water was prepared using a Milli-Q system (Millipore, Milford, MA, USA). Control rat plasma and urine were purchased from Innovative Research (Novi, MI, USA). Waymouth 752 culture medium...


Factors affecting the in vivo lactone stability and systemic clearance of the lipophilic camptothecin analogue AR-67

ED Adane, Z Liu, TX Xiang, BD Anderson... - ...research, 2010 - Springer
...Louis, MO). Dimethylsulfoxide (=99.7% DMSO) and glacial acetic acid came from Fisher Scientific (Fair Lawn, NJ). Blank rat plasma, used in the preparation of calibrators and quality control solutions, was from Innovative Research (Novi, Michigan).


Quantitative analysis of tissue folate using ultra high-performance liquid chromatography tandem mass spectrometry

J Liu, R Pickford, AP Meagher, RL Ward - Analytical Biochemistry, 2011 - Elsevier
...In the labeled standards, the 13 C 5 was present in the five carbons of the glutamate moiety (isotopic enrichment >99%). Rat plasma from Innovative Research (Novi, MI, USA) was used as a source of conjugase to hydrolyze folate polyglutamates.


Implications of plasma protein binding for pharmacokinetics and pharmacodynamics of the gamma-secretase inhibitor RO4929097

J Wu, PM LoRusso, LH Matherly... - Clinical Cancer Research, 2012 - AACRbr>...Louis, MO). Human, rat, mouse, and beagle plasma, and human blood were obtained from Innovative Research Inc. (Novi, MI). pGL3-Basic vector, pRL-SV40 expression construct, and the dual- luciferase reporter assay system were obtained from Promega (Madison, WI).


Simple, Sensitive, High-Throughput Method for the Quantification of Mitragynine in Rat Plasma Using UPLC-MS and Its Application to an Intravenous Pharmacokinetic ...

PK Vuppala, SP Boddu, EB Furr, CR McCurdy... - Chromatographia, 2011 - Springer
...Methyl t-butyl ether was purchased from EMD Chemicals Inc. (Darmstadt, Germany) and ammonium formate was purchased from Sigma-Aldrich (St. Louis, MO, USA). Rat plasma was purchased from Innovative Research (Peary Court Novi, MI, USA).


Stability of Caffeic Acid Phenethyl Amide (CAPA) in Rat Plasma

J Yang, SM Kerwin, PD Bowman... - Biomedical ..., 2011 - Wiley Online Library
...Heparinized male Sprague Dawley rat plasma was obtained from Innovative Research (Novi, MI, USA). Water used in the experiments was passed through a Millipore (Billerica, MA, USA) Milli-Q water purification system (18.2 MO).


Conventional liquid chromatography/triple quadrupole mass spectrometry based metabolite identification and semi-quantitative estimation approach in the ...

ZY Hu, RB Parker, VL Herring, SC Laizure - Analytical and bioanalytical ..., 2013 - Springer
...USA). Human carboxylesterase CES1b, CES1c and CES2 Supersomes were obtained from BD Gentest (San Jose, CA, USA). Blank rat plasma (heparin sodium) was purchased from Innovative Research (Novi, MI, USA).


Development and validation of a UPLC-MS/MS method for the determination of 7-hydroxymitragynine, a -opioid agonist, in rat plasma and its application to a ...

PK Vuppala, S Jamalapuram, EB Furr, CR McCurdy... - Biomedical ..., 2013
...Lawn, NJ, USA). The solvents used during this study were all HPLC grade. Rat plasma with sodium heparin was purchased from Innovative Research (Peary Court Novi, MI, USA). Liquid chromatography and mass spectrometry.


Effects of short-term portacaval anastomosis on the peripheral and brain disposition of the blood-brain barrier permeability marker sodium fluorescein in rats

IH Shaik, MK Miah, U Bickel, R Mehvar - Brain Research, 2013
...The effects of various bile acids on the f u of FL in plasma were investigated in an in vitro study. Drug-free, heparinized rat plasma (Innovative Research, Novi, MI) was spiked with LCA, CA, CDCA, or TCA at concentrations of 0, 18.75, 37.5, 75, or 150 M.


Preclinical in vitro & in vivo evaluation of 11C SNAP-7941the first PET tracer for the melanin concentrating hormone receptor

W Wadsak, M Mitterhauser - Nuclear Medicine and Biology, 2013
(No. IPLA-N) and pooled lithium-heparinised rat plasma (No. IRT-N) were purchased from Innovative Research (Novi, MI, USA). The porcine liver carboxylesterase (EC3.1.1.1) was obtained from Sigma Aldrich. Centrifugal Filter...


Novel oral anti-influenza drug candidate AV5080

AV Ivachtchenko, YA Ivanenkov, OD Mitkin - Journal of Antimicrobial , 2014
Pooled human plasma in sodium citrate, Sprague Dawley rat plasma and canine plasma (mixed breed) in Na 2 EDTA were obtained from Innovative Research (Novi, MI, USA). Universal buffer was obtained from pION-Inc.


A rapid LCMS/MS method for quantification of CSUOH0901, a novel antitumor agent, in rat plasma

RR Voggu, R Alagandula, X Zhou, B Su, B Zhong - Biomedical , 2014
SpragueDawley rat plasma K2 with specific lot numbers (10577-0106) was purchased from Innovative research (Novi, MI, USA). Calibration standard and quality control samples. Preparation of stock and working solutions.


Species-Dependent Chelation of 241Am by DTPA Di-Ethyl Ester

JE Huckle, MP Sadgrove, RJ Mumper, M Jay - Health Physics, 2015
...separation. The 241 Am(NO 3 ) 3 stock solution was obtained from Eckert & Ziegler Isotope Products (Valencia, CA, USA). Rat, beagle and human plasma were obtained from Innovative Research Inc. (Novi, MI, USA). Pierce...

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Sprague Dawley Rat Plasma

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