Human Serum

Single Donor Human Serum

Catalog No.: IPLA-SERS

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Category: Serum

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Product Description

Single Donor Human Serum

Innovative Research's Single Donor Human Serum is derived from whole blood which is obtained from FDA-approved facilities. The blood sample is allowed to clot, centrifuged, and the serum is isolated.

The material undergoes viral testing, and the final product is aliquoted to customer specifications. All lots have been tested by an FDA-approved method and found to be negative for Human Immunodeciency Virus RNA (HIV-1 RNA), Antibodies to Human Immunodeciency Virus (Anti-HIV 1/2), Antibodies to Hepatitis C Virus (HCV), Hepatitis C Virus RNA (HCV RNA), non- reactive for Hepatitis B Surface Antigen (HbsAg), and non-reactive by a screening test for syphilis.

This Innovative Research product is for in vitro research use only, is not to be consumed by animals or humans, and should be handled with general precaution as if capable of spreading infectious disease.

Immune reactivity against a variety of mammalian milks and plant-based milk substitutes

Aristo Vojdani, Chris Turnpaugh, and Elroy Vojdani
Journal of Dairy Research, August 2018

"... Five hundred sera from a cross-spectrum population aged 18-65 were obtained from Innovative Research (Novi, MI, USA). The healthy subjects were tested according to FDA guidelines for the detection of hepatitis B surface antigen, antibodies to HIV, HIV-1 RNA, Hepatitis-C RNA, and syphilis. All samples yielded non-reactive or negative results for each test performed..."

A rapid immunochromatography test based on Hcp1 is a potential point-of-care test for serological diagnosis of melioidosis

Phornpun Phokrai, Wisansanee Karoonboonyanan, Nida Thanapattarapairoj , Chidchanok Promkong, Adul Dulsuk, Sirikamon Koosakulnirand, Sasha Canovali, Nitaya Indrawattana, Yaowaruk Jutrakul, Vanaporn Wuthiekanun, Direk Limmathurotsakul, Paul J. Brett, Mary N. Burtnick, Ganjana Lertmemongkolchai, Narisara Chantratita
J. Clin. Microbiol.

... in 130 northeast Thailand; (iii) sera from healthy donors from the U.S. (N = 90) (Innovative Research, Novi, MI, USA); and (iv) sera from patients with culture results ...

Prevalence of Pre-existing Antibodies to CRISPR-associated Nuclease Cas9 in the US Population

Simhadri VL, McGill J, McMahon S, Wang J, Jiang H, Sauna ZE
Molecular Therapy: Methods & Clinical Development (2018)

... Serum samples from healthy donors were purchased from Innovative Research (Innovative Research, Novi, MI) and stored at -80oC until analysis. SaCas9 and SpCas9 proteins were custom-produced ...


An Improved Method for the Sensitive Detection of Shiga Toxin 2 in Human Serum

Xiaohua He, Gianluigi Ardissino, Stephanie Patfield, Luisa W. Cheng, Christopher J. Silva and Maurizio Brigotti
Toxins, 31 January 2018

... The human serum samples without Stx contamination were obtained from an FDA licensed commercial donor center and processed in an FDA registered facility (Innovative Research, Inc., Novi, MI, USA). Human serum samples were also collected from patients with a proven STEC-infection on admission to the clinic and frozen in aliquots at 20 C


Integrated dielectrophoresis and fluorescence-based platform for biomarker detection from serum samples

Logeeshan Velmanickam, Michael Fondakowski and Keerthi Nawarathna - IOPScience, Jan 4 2018

... used commercially available single donor human serum from Innovative TM Research (Novi, MI, USA). Innovative research's single donor human serum is derived from whole blood, which is obtained All the researchers who handle serum samples were trained on how to safely ...


NMR-Guided Mass Spectrometry for Absolute Quantitation of Human Blood Metabolites

G. A. Nagana Gowda, Danijel Djukovic, Lisa Fan Bettcher, Haiwei Gu, and Daniel Raftery - January 2, 2018.

... MA). Human serum samples from 8 healthy subjects (4 Male; 4 Female; Table S1) were obtained from Innovative Research, Inc (Novi, MI). A commercial pooled human serum was also obtained from Innovative Research, Inc. Deionized (DI) water was purified using an in-house ...


Gluten and Non-Gluten Proteins of Wheat as Target Antigens in Autism, Crohns and Celiac Diseases

A Vojdani, E Vojdani - Journal of Cereal Science, 2017
... Forty-eight sera from healthy control subjects aged 18-65 were obtained from Innovative Research (Novi, MI, USA). Commercially available sera of 24 ...


Comparison of O-polysaccharide and hemolysin co-regulated protein as target antigens for serodiagnosis of melioidosis

A Pumpuang, SJ Dunachie, P Phokrai, K Jenjaroen - PLOS Neglected Tropical , 2017
... who were admitted to Sappasithiprasong hospital, Ubon Ratchathani, northeast Thailand, 188 serum samples obtained from healthy donors from the same area in northeast Thailand and 90 serum samples obtained from healthy US donors (Innovative Research, Novi, MI, USA ...


Two-photon polymerization for production of human iPSC-derived retinal cell grafts

KS Worthington, LA Wiley, EE Kaalberg, MM Collins - Acta Biomaterialia, 2017
.... dissociated and resuspended individual iPSC colonies derived from a donor with normal ocular history in 3D differentiation medium DMEM (Gibco, Thermo Fisher Scientific, Grand Island, NY), 10% heat-inactivated human serum (Innovative Research, Novi, MI) 20% CTS ...


PDF Development of rapid ELISAs for detection of antibodies to Burkholderia pseudomallei

V Suttisunhakul, V Wuthiekanun, PJ Brett, S Khusmith - Journal of Clinical , 2016
... healthy donors from the same area in northeast Thailand and 90 serum samples obtained from 126 healthy US donors (Innovative Research, Novi, MI, USA). Another three sets of on- 127 admission anonymous human sera were used to further evaluate the specificity of the 128 ...


HTML Cross-kingdom inhibition of breast cancer growth by plant miR159

AR Chin, MY Fong, G Somlo, J Wu, P Swiderski, X Wu - Cell Research, 2016
...and subjected to reverse transcription (RT)-qPCR for miR159 and miR-16 as described 7 . Individual and pooled healthy female donor human sera were purchased from Innovative Research (Novi, MI). ...


IgG Subclasses and Isotypes of VH4-34 Encoded Antibodies

NM Bhat, MA Kshirsagar, MM Bieber, NNH Teng - Immunological Investigations, 2015
... A total of 33 female and 33 male normal adult serum samples were analyzed as controls (Innovative Research, Novi, MI, Bioreclamation, Hicksville, NY and laboratory personnel).ELISA for VH4-34 Encoded IgM, IgA and IgG Subclass ...



SP accession No, N accession No, D Glycoprotein - Genome
... Samples were stored at 70C. Purchased sera from 60 healthy donors (Innovative Research Inc., Novi, MI, USA) were included as controls. This study was approved by the Institutional Review Board of Severance Hospital, Yonsei University College of Medicine, Seoul, Korea...


Determination of triapine, a ribonucleotide reductase inhibitor, in human plasma by liquid chromatography tandem mass spectrometry

Y Feng, CA Kunos, Y Xu - Biomedical Chromatography, 2015
Six lots of human blank plasma (EDTA-treated), six lots of human blank sera, and pooled human blank plasma were purchased from Innovative Research (Novi, MI, USA). Preparation of stock and standard solutions...


Increasing Serum Soluble Angiotensin-Converting Enzyme 2 Activity After Intensive Medical Therapy Is Associated With Better Prognosis in Acute Decompensated

Z Shao, K Shrestha, AG Borowski, DJ Kennedy... - Journal of Cardiac Failure, 2013
...5 Donor human serum (Innovative Research, Novi, Michigan) and patients' serum samples were diluted in a ratio of 3:7 (sample:buffer) with enzyme buffer (1 mol/L NaCl, 75 mmol/L Tris-HCl, 0.5 mmol/L ZnCl 2 , pH 6.5) in the presence of protease inhibitors, including 10 mol/L...


15N-CholamineA Smart Isotope Tag for Combining NMR-and MS-Based Metabolite Profiling

F Tayyari, GAN Gowda, H Gu, D Raftery - Analytical Chemistry, 2013
...further purification. Human serum samples were obtained from Innovative Research, Inc. (Novi, MI) and urine from healthy volunteers, in accordance with the Internal Review Board at Purdue University. Deionized (DI) water...


Serum IgA reactivity against GroEL of Streptococcus sanguinis and human hnRNP A2/B1 in patients with Behet's disease

SB Cho, Z Zheng, KJ Ahn, MJ Choi, S Cho, DY Kim... - British Journal of ..., 2012
...criteria with or without any number of minor criteria. Purchased sera from 70 healthy donors (Innovative Research Inc., Novi, MI, USA) were used as controls. All of the serum samples were stored at -70C. Medical records of....


Add to Subtract: A Simple Method to Remove Complex Background Signals from the 1 H Nuclear Magnetic Resonance Spectra of Mixtures

D Raftery, T Ye, C Zheng, S Zhang, NA Gowda... - Analytical ..., 2012 - ACS Publications
subject with diabetes. Sample set 2: A human serum sample was purchased from Innovative Research (Novi, MI) and aliquoted. One aliquot was used without further processing for CPMG experiments. For comparison, proteins...


A comprehensive compositional analysis of heparin/heparan sulfate-derived disaccharides from human serum

W Wei, MR Ni onuevo, A Sharma... - Analytical ..., 2011 - ACS Publications
Human sera from female single donors (Hispanic age of 29, African American age of 44 and Caucasian age of 38) were obtained from Innovative Research (Novi, MI). Human Serum Fractionation and Digestion. A sample of 20 L human serum was diluted to 4...


Development and validation of an LC-MS/MS method for determination of phencyclidine in human serum and its application to human drug abuse cases

KC Chimalakonda, C Hailey, R Black, A Beekman... - Anal. Methods, 2010 - xlink.rsc.org
Drug free human serum from individual donors was purchased from Innovative Research (Novi, MI). Drug free human whole blood was obtained from the Clinical Laboratory at the University of Arkansas Hospital (Little Rock, AR)


Sensitive liquid chromatography/tandem mass spectrometry assay for absolute quantification of ITIH4-derived putative biomarker peptides in clinical serum samples

I van den Broek, RW Sparidans... - Rapid ..., 2010 - Wiley Online Library
...Bovine plasma with sodium citrate as anticoagulant and blank human serum (batch A) were obtained from Innovative Research (Novi, MI, USA) whereas blank human plasma was obtained from the Sanquin Bloodbank (Utrecht, The Netherlands).


Application of 31P NMR spectroscopy and chemical derivatization for metabolite profiling of lipophilic compounds in human serum

MA DeSilva, N Shanaiah... - Magnetic ..., 2009 - Wiley Online Library
from Sigma-Aldrich (St. Louis, MO) and used without further purification. Deuterated solvents were purchased from Cambridge isotope (Andover, MA). Human serum samples were obtained from Innovative Research (Novi, MI)

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Single Donor Human Serum

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