Recombinant Mouse Kallikrein
Recombinant insect cell derived mouse kallikrein is a serine protease which consists of a heavy chain and light chain linked by disulfide bonds. Kallikrein is activated from prekallikrein with Factor XIIa followed by repurification by affinity chromatography. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. Mouse Kallikrein is >95 percent pure by SDS-PAGE and shows total reduction upon incubation with 2-mercaptoethanol. Specific activity is determined via complementation in an APTT clotting assay using prekallikrein immuno-deficient human plasma.