Recombinant Mouse Factor XIIa
Recombinant Mouse Factor XIIa is a serine protease responsible for the activation of Factor XI to XIa in the contact activation system of blood coagulation. Recombinant insect cell derived mouse Factor -XIIa is manufactured by autoactivation of recombinant mouse Factor XII with Dextran Sulfate and re-purified to remove the activator. >95 percent activation is observed on SDS-PAGE. The protein purity is determined by SDS-PAGE and activity is determined via complementation in an APTT clotting assay using Factor XII immuno-deficient human plasma.