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Rat PAI-1 Proteins

Rat PAI-1 NBD Labeled at the Scissile Bond of the Reactive Center Loop

Catalog No.: IRPAI-P1NBD

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$895

Category: Proteins

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Rat PAI-1 NBD labeled at the scissile bond of the reactive center loop


P1'-NBD rat PAI-1 was created by mutagenesis of the methionine residue (Met348) at the P1-P1' scissile bond to cysteine. This provides a free thiol group for labeling with NBD, a fluorescent probe highly sensitive to changes in solvation and hydrophobic environment. The fluorescence emission of P1'-NBD PAI-1 is quenched upon cleavage of the reactive center loop by a target proteinase. This unique product is an ideal reagent for researchers studying PAI-1 behavior in rat models.

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Rat PAI-1 NBD Labeled at the Scissile Bond of the Reactive Center Loop

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