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Mouse Cystatin Assay and ELISA Kits

Mouse Cystatin C ELISA Kit

Catalog No.: IRAPKT3107

$525

Category: Assay and ELISA Kits

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Product Description

Mouse Cystatin C ELISA Kit


Our Mouse Cystatin C ELISA Kit is a sandwich ELISA intended for the quantitative determination of mouse Cystatin C in cell culture supernates, serum, plasma (heparin, EDTA) and urine.

Cystatin C or cystatin 3(formerly gamma trace, post-gamma-globulin or neuroendocrine basic polypeptide), a protein encoded by the CST3 gene, was originally described as a constituent of normal cerebrospinal fluid(CSF) and of urine from patients with renal failure. Cystatin 3 has a low molecular weight(approximately 13.3 kilodaltons), and it is removed from the bloodstream by glomerular filtration in the kidneys. In mouses, all cells with a nucleus(cell core containing the DNA) produce cystatin C as a chain of 120 amino acids. It is found in virtually all tissues and bodily fluids. Cystatin C, which belongs to the type II cystatin gene family, is a potent inhibitor of lysosomal proteinases(enzymes from a special subunit of the cell that break down proteins) and probably one of the most important extracellular inhibitors of cysteine proteases(it prevents the breakdown of proteins outside the cell by a specific type of protein degrading enzymes). Moreover, cystatin C is involved in network reorganization in the epileptic dentate gyrus.

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Mouse Cystatin C ELISA Kit

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