Human tPA Assay and ELISA Kits

Human tPA ELISA Kit

Catalog No.: IHTPAKT


Category: Assay and ELISA Kits

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Product Description

Human tPA ELISA Kit

The Human tPA ELISA Kit is for the sensitive measurement of functionally active human tPA. Active tPA will bind to biotinylated functionally active PAI-1 bound to the avidin coated microtiter plate. Only free active enzyme will react with the PAI-1 on the plate. Inactive or complexed enzyme will not be detected. An HRP detection system using TMB substrate is used for color development at 450nm. A standard calibration curve is prepared using dilutions of purified tPA and is measured along with the test samples.

Tissue plasminogen activator (tPA) is a serine protease that catalyzes the activation of plasminogen to plasmin. Clinical studies have indicated that high tPA levels may increase the risk for thrombosis, whereas decreased levels may cause neuronal plasticity and degeneration.

Activated Protein C Prevents Postsurgical Adhesion Band Formation

P Dinarvand, SM Hassanian, H Weiler, AR Rezaie
... The ELISA kit for measuring the concentration of tissue plasminogen activator (tPA) was obtained from Innovative Research Inc. Page 5. 5 (Novi, MI). ... Innovations, Inc., Royal Oak, MI) was analyzed by a kinetic assay as described.8 Statistical analysis ...


Placenta growth factor (PlGF), a novel inducer of plasminogen activator inhibitor-1 (PAI-1) in sickle cell disease (SCD)

N Patel, N Sundaram, M Yang, C Madigan... - Journal of Biological ..., 2010 - ASBMB
...Tissue plasminogen activator (tPA) levels in plasma were determined using ELISA as per the manufacturer's instructions (Innovative Research, Novi, MI). Data are expressed as mean SE of three independent experiments with duplicate samples.


Long-term stability of recombinant tissue plasminogen activator at-80 C

G Shaw, M Sperling... - BMC research notes, 2009 - biomedcentral.com
...sample. The samples were assayed for tPA activity using an ELISA technique that measures active tPA using plasminogen activator inhibitor 1 (PAI-1) (Human tPA Activity Assay, IHTPAKT, Innovative Research, Novi, MI, USA). In...

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Human tPA ELISA Kit

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