Single Donor Human Red Blood Cells
Innovative Research's Single Donor Human Red Blood Cells are separated from one unit of single donor human whole blood collected in CPDA-1 Anticoagulant. These cells are not washed or re-suspended. This product is custom collected, and donor specifications can be requested. All human blood products sold by Innovative Research are collected at FDA-licensed commercial donor centers within the US.
Each unit has been tested by FDA-approved methods and found to be negative for Human immunodeficiency Virus RNA (HIV-1 RNA), Antibodies to Human Immunodeficiency Virus (Anti-HIV 1/2), Antibodies to Hepatitis C Virus (HCV), Hepatitis C Virus RNA (HCV RNA), non reactive for Hepatitis B Surface Antigen (HbsAg), and non-reactive by a screening test for syphilis.
Human whole blood products are drawn fresh for each order and generally take 2 to 3 days to clear all FDA-required viral markers.
This material is sold for in-vitro use only in manufacturing and research. This material is not suitable for human use. It is the responsibility of the user to undertake sufficient verification and testing to determine the suitability of each products application. The statements herein are offered for informational purposes only and are intended to be used solely for your consideration, investigation and verification.
Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acidsJournal of Controlled Release Volume 286, 28 September 2018, Pages 46-54
Sam Chen, Josh Zaifman, Jayesh A. Kulkarni, Igor V. Zhigaltsev, Ying K. Tam, Marco A. Ciufolini, Yuen Yi C. Tam, Pieter R. Cullis
"... The ability of LNP to cause hemolysis was assessed as follows. Briefly, human erythrocytes (RBC) (Innovative Research, Novi, MI) were washed three times with cold isotonic saline (0.9% w/v NaCl in water) and resuspended in pH 7.4 PBS to a final concentration of 4% vol/vol. LNP (with or without LD003) were then incubated with the RBC solution for 1 h at 37 degrees C..."(3-10-18)
Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved deliveryWei-Lun Tang, Wei-Hsin Tang, Andras Szeitz, Jayesh Kulkarni, Pieter Cullis, Shyh-Dar Li
Biomaterials, Volume 166, June 2018, Pages 13-26
... Sepharose CL-4B, and Sephadex G-50 were purchased from Fisher Scientific (Ottawa, ON, Canada). Human and sheep red blood cells (RBCs) for hemolysis test were purchased from Innovative Research (Novi, MI). DiIC18 ...
Antibacterial and Antibiofilm Activities of a Novel Synthetic Cyclic Lipopeptide Against Cariogenic Streptococcus mutans UA159
Kyung R. Min, Adriana Galvis, Brandon Williams, Ramanjaneyulu Rayala, Predrag Cudic, and Dragana Ajdic, Antimicrobial Agents, 2017
... included three biological replicates. 214 215 Hemolytic activity assay. Human red blood cells (hRBCs, Innovative Research, Novi, MI) 216 were diluted in PBS to 1% and dispensed in clear, flat-bottom 96-well plates at a volume 217 of 50 l per well. ...
R Xu, W Sun, J Jin, LM Obeid, C Mao - The FASEB Journal, 2010 - FASEB
...instructions and the method of Hanel et al. (22)? . Human erythrocytes were purchased from Innovative Research (Novi, MI, USA), and further purified by the Ficoll gradient procedure as described above. siRNA transfection... (7-12-10)
J Stamler - 2010 - dukespace.lib.duke.edu
...Materials and Methods Hemoglobin (Hb). Hb was purified from human RBCs obtained from Innovative Research (Novi, MI), following the procedure of Geraci et al.12 Hb was stored in an aqueous solution at -80 C for later usage. (9-7-10)
Development of two animal models to study the function of Vibrio parahaemolyticus type III secretion systems
P Pieyro, X Zhou, LH Orfe, PJ Friel... - Infection and ..., 2010 - Am Soc Microbiol
...Human red blood cells or erythrocytes (HRBCs) (2% suspension in Alsever solution from a single donor; Innovative Research, Novi, MI) were pelleted, washed four times, and resuspended in an equal volume of phosphate-buffered saline (PBS) (pH 7.4) before they were added... (6-20-12)
Direct access to side chain N, N'-diaminoalkylated derivatives of basic amino acids suitable for solid-phase peptide synthesis
JP Pitteloud, N Bionda, P Cudic - Amino Acids, 2012 - Springer
...Microplate reader (Awareness Technology Inc., Palm City, FL). Human red blood cells (hRBCs) were purchased from Innovative Research (Novi, MI). Human serum was purchased from Sigma Aldrich (St. Louis, MO). NMR analysis... (1-3-13)
S Sankaranarayanan, M de la Llera-Moya... - Journal of Lipid Research, 2013
...Louis, MO). Fatty acid-free BSA was purchased from Millipore (Kankakee, IL) and egg L-a-phosphatidylcholine (egg PC) was from Avanti Polar Lipids (Alabaster, AL). Red blood cells were purchased from Innovative Research, Inc (Novi, MI) and (1, 2-...