Human Elastase Proteins

Human Neutrophil Elastase

Catalog No.: IHNE



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Human Neutrophil Elastase

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Human Neutrophil Elastase is chromatographically purified from human leukocytes. The neutrophil form of elastase is 218 amino acids long, with two asparagine-linked carbohydrate chains. No detectable amounts of Cathepsin G or MPO.Human Neutrophil(s), also known as neutrophilic polymorphonuclear leukocytes, are the major class of white blood cell in human peripheral blood. Human Neutrophil(s), have a multilobed nucleus and neutrophilic granules. Neutrophil(s) are phagocytes and have an important role in engulfing and killing extracellular pathogens.

Enzymatically Degradable Mussel-Inspired Adhesive Hydrogel

CE Brubaker, PB Messersmith - Biomacromolecules, 2011 - ACS Publications
...(Owensville, MO). Decellularized porcine dermis extracellular matrix was generously supplied by Kensey Nash Corp. (Exton, PA). Human neutrophil elastase (HNE) was purchased from Innovative Research (Novi, MI). Mouse...


Inhibition of Human Neutrophil Elastase by Pentacyclic Triterpenes

L Feng, X Liu, W Zhu, F Guo, R Wang, K Chen - PLOS ONE, 2013
Materials and Methods. Materials and Test Compounds. HNE (EC from human leukocytes was purchased from Innovative Research Company (Novi, Michigan). ONO-5046, HNE substrate (MeO-Suc-Ala-Ala -Pro-Val...


Cecropin A-melittin mutant with improved proteolytic stability and enhanced antimicrobial activity against bacteria and fungi associated with gastroenteritis in vitro

S Ji, W Li, L Zhang, Y Zhang, B Cao - Biochemical and Biophysical Research, 2014
Louis, MO), pepsin (Sigma), human neutrophil elastase (HNE; Innovative Research, Novi, MI), P. aeruginosa elastase (PE; Innovative Research), and S. aureus V8 protease (V8; BioCol GmbH) with a substrate: enzyme molar ratio of 300:1 at 37 C for 30 min.


Synthesis and biological evaluation of nigranoic acid esters as novel human neutrophil elastase inhibitors

G Huang, L Feng, B Liu, Y He, Y Li, Y Chen - Natural Product Research, 2015
HNE activity inhibitory bioassay. HNE (EC from human leucocytes was purchased from Innovative Research Company (Novi, Michigan). ONO-5046,HNE substrate (MeOSucAlaAlaProValpNA), soybean...


Improved production of sublancin via introduction of three characteristic promoters into operon clusters responsible for this novel distinct glycopeptide biosynthesis

S Ji, W Li, AR Baloch, M Wang, B Cao - Microbial Cell Factories, 2015
Aliquots of 5 mg/L sublancin in PBS (pH 7.4) were treated under different protease HNE (Innovative Research, Novi, MI), PE (Innovative Research), pepsin (Sigma), V8 (BioCol GmbH), and trypsin (Sigma Chemical Co., St. Louis

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Human Neutrophil Elastase

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