x
Human Kallikrein Proteins

Human Kallikrein

Catalog No.: IHKa

$475

Size

  • Choose An Option...

$475

Category: Proteins

  • Description

  • SDS

  • References

  • Sample Datasheet

  • Info Request

Product Description

Human Kallikrein


Activation of Prekallikrein with Factor a-XIIa produces the enzymatically active Kallikrein. Kallikrein is a serine protease which consists of a heavy chain (Mr 52kD) and light chains (Mr either 36 or 33 kD) linked by disulfide bridges. Kallikrein possesses enzymatic activity toward Factor XII, HK, Plasminogen, Factors XI, IX, and VII, prorenin and the complement system. After activation, the activating enzyme Factor XIIa is removed by affinity chromatography. Human Kallikrein purity is determined by SDS-PAGE and shows complete reduction upon incubation with 2-mercaptoethanol.
(5-23-11)

Cleavage of Kininogen and Subsequent Bradykinin Release by the Complement Component: Mannose-Binding Lectin-Associated Serine Protease (MASP)-1


J Dob, B Major, KA Kkesi, I Szab, M Megyeri... - PloS one, 2011 - dx.plos.org
...Human Kallikrein was purchased from Calbiochem (Darmstadt, Germany), or Innovative Research (Novi, MI): both of them were about the same good quality. Human plasma kallikrein (referred to as kallikrein) and human plasma prekallikrein...

Contact Us About This Product

Human Kallikrein

© 2018 Innovative Research. All Rights Reserved.