Human Plasma Proteins

Human High Purity Apolipoprotein A1 (ApoA1), Plasma

Catalog No.: IRHPL0059



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Category: Plasma Proteins

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Human High Purity Apolipoprotein A1 (ApoA1), Plasma

Apo-AI comprises 70% of the protein moiety in HDL. It is a single polypeptide chain consisting of 245 amino acids with glutamic acid as the C-terminal residue and aspartic acid as the N-terminal residue. The molecular mass is reported to be 28.3 kDa. The protein is made up of one major isoform (pI 5.6) and two minor isoforms (pI 5.53 and 5.46). Apo-AI shows a high content of a-helix structure. The amphipathic regions in the helix structure seem to be responsible for lipid binding capacity. In aqueous solution, Apo-AI shows self-association with minor conformation change. Apo-AI activates lecithin-cholesterol (LCAT) acyltransferase, which is responsible for cholesterol esterification in plasma.

This product is for in vitro research use only, is not to be consumed by animals or humans, and should be handled with general precaution as if capable of spreading infectious disease.

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Human High Purity Apolipoprotein A1 (ApoA1), Plasma

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