Human Hormone Assay and ELISA Kits

Human Hemopexin ELISA Kit (Plasma and Serum)

Catalog No.: IRKTAH2562


Category: Assay and ELISA Kits

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Product Description

Human Hemopexin ELISA Kit (Plasma and Serum)

Human Hemopexin ELISA Kit is designed for detection of human hemopexin in plasma and serum. This assay employs a quantitative competitive enzyme immunoassay technique that measures human hemopexin in less than 2 hours. A polyclonal antibody specific for human hemopexin has been pre-coated onto a 96-well microplate with removable strips. Hemopexin in standards and samples is competed by a biotinylated hemopexin sandwiched by the immobilized antibody and streptavidin-peroxidase conjugate. All unbound material is then washed away and a peroxidase enzyme substrate is added. The color development is stopped and the intensity of the color is measured.

Hemopexin is a heme-binding plasma glycoprotein which, after haptoglobin, forms the second line of defense against hemoglobin-mediated oxidative damage during intravascular hemolysis. A decrease in plasma hemopexin concentration reflects a recent release of heme compounds in the extracellular compartment. Hemehemopexin complexes are delivered to hepatocytes by receptor-mediated endocytosis after which hemopexin is recycled to the circulation (1). Studies indicated that increased hemopexin level associate with minimal change disease (MCD) (2), sporadic Alzheimer's disease (AD) (3), heavy-drinking chronic alcoholics (4), hemolytic anemias, chronic neuromuscular diseases and acute intermittent porphyria (5).

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Human Hemopexin ELISA Kit (Plasma and Serum)

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