Human Factor XIII Proteins

Human Coagulation Factor XIII

Catalog No.: IHFXIII

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Category: Proteins

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Product Description

Human Coagulation Factor XIII

Human Factor XIII is a tetramer composed of two pairs of chains held together by noncovalent bonds. After activation of the zymogen via thrombin to its active enzyme form, Factor XIIIa is responsible for catalyzing the formation of covalent bridges between fibrin units to increase the elasticity of the clot network. The resulting cross-linked fibrin is very insoluble and resistant to lysis.

Cohesive behavior of soft biological adhesives: Experiments and modeling

AK Dastjerdi, M Pagano, MT Kaartinen... - Acta ..., 2012 - barthelat-lab.mcgill.ca
...Fibrin was prepared as de- scribed above, and crosslinking of fibrin was induced by adding human Factor XIII (Innovative Research, Novi, MI, USA) to the fibrinogen solution and then combining and mixing it with the thrombin solution. In addition to inducing fibrin formation from...


Comparative characterization of direct and indirect substrate probes for on-chip transamidating activity assay of transglutaminases

K Lee, SH Jung, DH Kong, BM Hwang, ET Han... - Journal of Biotechnology, 2013
... from Sigma-Aldrich (St. Louis, MO). Purified guinea pig TG2 was purchased from Oriental Yeast (Tokyo, Japan). Purified human plasma FXIII was obtained from Innovative Research (Novi, MI). 5-(Biotinamido) pentylamine (biotin...

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Human Coagulation Factor XIII

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