Human Ceruloplasmin ELISA Kit
The Human Ceruloplasmin ELISA kit is intended for the quantitative determination of total ceruloplasmin antigen in human plasma, serum, urine, milk, saliva and cell culture samples. This assay employs a quantitative competitive enzyme immunoassay technique that measures human ceruloplasmin in less than 3 hours. Ceruloplasmin is an abundant 2-serum glycoprotein that contains 95% of the copper found in the plasma of vertebrate species (1). Ceruloplasmin is a copper-binding protein that normally removes iron from cells by its ferroxidase activity. Ceruloplasmin concentration on average is 14.6 (4.0) mg/dl. Low levels of ceruloplasmin lead to the abnormal deposits of iron in cells, including those of the pancreas, liver, retina and the basal ganglia region of the brain. Some diseases associated with ceruloplasmin are Wilson's disease (3), Hemochromatosis (4), Menkes disease (5) and Aceroluplasminemia (1).