Human Apolipoprotein B (ApoB)
Innovative Research's Human Apolipoprotein B(ApoB) are the primary apolipoproteins of chylomicrons and low-density lipoproteins (LDL), which are responsible for carrying cholesterol to tissues. While it is unclear exactly what functional role APOB plays in LDL, this primary apolipoprotein component is absolutely required for its formation. What is clear is that the APOB on the LDL particle acts as a ligand for LDL receptors in various cells throughout the body (i.e. less formally, APOB "unlocks" the doors to cells and thereby delivers cholesterol to them). Through a mechanism that is not fully understood, high levels of APOB can lead to plaques that cause vascular disease, called atherosclerosis, which leads to heart disease. There is considerable evidence that levels of APOB are a better indicator of heart disease risk than total cholesterol or LDL.
This product is for in vitro research use only, is not to be consumed by animals or humans, and should be handled with general precaution as if capable of spreading infectious disease