Human Macroglobulin Plasma Proteins

Human Alpha-2 Macroglobulin (A2M)

Catalog No.: IRHPL0044



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Category: Plasma Proteins

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Product Description

Human Alpha-2 Macroglobulin (A2M)

Innovative Research's Human Alpha 2 Macroglobulin (A2M) is a major serum protein found at concentrations of 240 mg per 100 ml in men and 290 mg per 100 ml in women. Multifunctional, it promotes growth of mammalian cells in culture, stimulates the regeneration of lymphocytes in irradiated mice, possesses a transport function for zinc, and is a proteinase inhibitor that controls the clotting and fibrinolytic systems. Clinically, levels are increased in liver cirrhosis, nephrotic syndrome, diabetes, and severe burn cases.

Prepared from plasma shown to be non-reactive for HbsAG, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-approved tests. >95percent pure by SDS-PAGE. Add deionized water to original volume, aliquot and freeze unused portion.

This product is for in vitro research use only, is not to be consumed by animals or humans, and should be handled with general precaution as if capable of spreading infectious disease.

A novel hemostasis assay for the simultaneous measurement of coagulation and fibrinolysis

M Geffen, A Loof, P Lap, J Boezeman... - ..., 2011 - ingentaconnect.com
...Reptilase was from Diagnostica Stago, Parsippany, NJ, USA. Alpha 2 -macroglobulin (a 2 M) was purchased from Innovative Research, Peary Court, Novi, MI, USA. Thrombomodulin (TM) was from American Diagnostics, Stanford, CT, USA.

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Human Alpha-2 Macroglobulin (A2M)

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