Rat sE-Selectin ELISA Kit

Catalog No.: IRKTAH5533


Category: Assay and ELISA Kits

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Product Description

Rat sE-Selectin ELISA Kit - 1 Kit (96 Wells)

Our Rat sE-Selectin ELISA Kit is a sandwich ELISA intended for the quantitative determination of rat soluble E-Selectin in cell culture supernates, serum and plasma (heparin, citrate).

E-selectin, also called endothelial-leukocyte adhesion molecule-1(ELAM-1), is a cell surface glycoprotein expressed by cytokine-activated endothelium that mediates the adhesion of blood neutrophils.1 An increased expression of E-selectin has been observed in the arterial endothelium interacting with lymphocytes and macrophages in human atherosclerotic lesions.2 E-selectin plays a critical role in mediating tissue-specific homing of T cells into skin, and of primitive hematopoietic progenitor cells(HPCs) into bone marrow(BM).3 A structurally and functionally related group of genes, lymph node homing receptor(LHR), granule membrane protein 140(GMP-140), and endothelial leukocyte adhesion molecule 1(ELAM-1) are shown to constitute a gene cluster on mouse and human chromosome 1.4

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Rat sE-Selectin ELISA Kit

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